Results 171 to 180 of about 612,190 (327)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Characterizing the Fracture Forming Limit Curve from Shear to Uniaxial Tension in Ultrathin Sheet Metals Using Specimens with Cutouts

, 2023
Nan Gu, Xiaoliang Luo, Wen Zhang, Xincun Zhuang, Zhen Zhao   +4 more
openalex   +1 more source

Characterisation and optimisation of a failure model for high strength aluminium alloys using Nakajima experiments [PDF]

, 2018
Harrison, David, Kulatunga, Muditha, MacDonald, Martin, Mouchtar, Serkan, Rimkus, Wolfgang, Schanz, Jochen, Schlosser, Julian, Schneider, Robert   +7 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Numerical and statistical analysis of aluminum deep drawing using LS-DYNA coupled with Taguchi design and response surface methodology. [PDF]

Sci Rep
Shamso E, El Kafy MA, Naeim N.
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Central limit theorems for elliptic curves and modular forms with smooth\n weight functions [PDF]

, 2019
Stephan Baier, Neha Prabhu, Kaneenika Sinha   +2 more
openalex   +2 more sources

Polymer additive manufacturing tools for sheet metal forming: a combined simulation and experimental study. [PDF]

Sci Rep
Bhatia CV, Patel D, Vats R, Zameer MMF, Kumar R, Rajhi AA, Duhduh AA, Lozanovic J.   +7 more
europepmc   +1 more source

Forming Limit Curve Determination of a DP-780 Steel Sheet

, 2015
Claudio Schwindt, Mike Stout, L. Iurman, Javier H. Signorelli   +3 more
openalex   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source