An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu +14 more
wiley +1 more source
Key elements and theoretical logic of application of PIC/S standards in improving drug GMP inspections in China: an analysis based on grounded theory. [PDF]
Hu D, Liao P, Chen Y.
europepmc +1 more source
A mechanically tunable hydrogel composed of gelatin, chondroitin sulfate and laminin promotes angiogenesis in vitro without the supplement of growth factors. Endothelial cells morphogenesis was further enhanced by medium conditioned with bioactive glass 58S‐released ions (Ca and Si), thus offering a promising strategy to vascularize 3D tissue ...
Marco Piazzoni +13 more
wiley +1 more source
Global Pharmaceutical Regulation: Comparative Frameworks and Operations. [PDF]
Umaru OT +6 more
europepmc +1 more source
The Effect of Purcell Cavities on the Lifetime of Thermally Activated Delayed Fluorescent Emitters
A pressing challenge to OLED displays and lighting is to balance high efficiency and long operational lifetime in the deep blue spectrum. The Purcell effect can reduce the triplet density and hence the probability for destructive energy‐driven triplet annihilation events that limit the OLED lifetime. Here we study of the Purcell effect on two different
Sritoma Paul +4 more
wiley +1 more source
Fear of falling among housebound older adults: a quantitative study. [PDF]
Yang K +5 more
europepmc +1 more source
Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu +3 more
wiley +1 more source
Governance and policy in global neurosurgery: a scoping review of national and international efforts. [PDF]
Dos Santos Rubio E +7 more
europepmc +1 more source
Control of Polarization and Polar Helicity in BiFeO3 by Epitaxial Strain and Interfacial Chemistry
In BiFeO3 thin films, the interplay of interfacial chemistry, electrostatics, and epitaxial strain is engineered to stabilize homohelicity in polarization textures at the domain scale. The synergistic use of a Bi2O2‐terminated Aurivillius buffer layer and a highly anisotropic compressive epitaxial strain offers new routes to control the polar‐texture ...
Elzbieta Gradauskaite +5 more
wiley +1 more source
The Statistical Agencies of the Federal Government: A Report to the Commission on Organization of the Executive Branch of the Government [PDF]
Clarence D. Long, Frederick C. Mills
core +3 more sources

