Results 41 to 50 of about 10,817 (262)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Jurnal Ilmiah Ilmu Administrasi Publik, 2020 This study aimed (1) to analyze the role of research results in the formulation of border management policies in North Central Timor Regency conducted by the Regional Border Management Agency of North Central Timor Regency and (2) to analyze the obstacles faced by the Regional Border Management Agency in applying research results in the process of the ...
Yohanes Fritantus, Makarius Erwin Bria
openaire +3 more sources
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
LABOR RESOURCES AND LABOR UTILIZATION IN VINH CITY, NGHE AN PROVINCE IN THE PERIOD 2012-2022
Tạp chí Khoa họcLabour resources and employment are top concerns in the socio-economic development strategies of every country and locality on the path of development. This article analyses and clarifies the current state of labour resources and employment in Vinh City
Phan Thi Van
doaj +1 more source
Zeszyty Naukowe Wyższej Szkoły Finansów i Prawa w Bielsku-Białej, 2023 This article delves into the multifaceted landscape of local government employees' job decisions (JD) and job engagement (JE) by investigating their tenure intentions.
Włodzimierz Strelcow +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Research progress on evaluation index system of nursing quality in nursing homes
Huli yanjiu, 2018 This paper introduced the research on the evaluation index system of nursing quality in nursing home institutions at home and abroad,analyzed the problems in the quality of nursing services in pension agencies in China,and aiming to draw lessons from ...
王春霞, 纪代红, 李亮
doaj
Faculty Development in Medical Education in India: [PDF]
Al Ameen Journal of Medical Sciences, 2009 Medical education in India is challenged with the shortage of teachers. The teachers are not adequately prepared to handle tasks in response to the emergent needs.
D.K. Srinivas, B.V.Adkoli
doaj
Research to guide management of outdoor recreation and tourism in parks and protected areas
Koedoe: African Protected Area Conservation and Science, 2014 A framework for managing outdoor recreation and tourism in parks and protected areas was presented in this article. This management-by-objectives framework includes, (1) formulating indicators and standards of quality, (2) monitoring indicators of ...
Robert E. Manning
doaj +1 more source