Results 41 to 50 of about 12,045 (305)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Dissemination of statistical information in Brazil: experiences and politics of the State agencies of statistics [PDF]
, 2015 Statistical information is essential for planning, formulating projects and public politics, consequently to the development of State. In this context it was analysed the present characteristics, progress and challenges of the state agencies which belong
Gracioso, Luciana de Souza
core +1 more source
, 2022 The aim of this study is to determine the mediating effect of strategy implementation of the relationship between TMT characteristics and performance of Ugandan state agencies. The study was anchored on the upper echelons’ theory and dynamic capabilities
Nuwagaba, Arthur +3 more
core +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Jurnal Ilmiah Ilmu Administrasi Publik, 2020 This study aimed (1) to analyze the role of research results in the formulation of border management policies in North Central Timor Regency conducted by the Regional Border Management Agency of North Central Timor Regency and (2) to analyze the obstacles faced by the Regional Border Management Agency in applying research results in the process of the ...
Yohanes Fritantus, Makarius Erwin Bria
openaire +3 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Formulating good governance and moving forward: Navigating transparency or reinforcing authority and power? [PDF]
, 2017 In reshaping and strengthening the state in its exercise of wide-ranging influences by entrenched interests either by the state, bureaucrats or for the citizens, there is confounding complexity made more so by the rapid expansion of networking and social
Loo-See, B.
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Validating SERVPERF model in government agencies. [PDF]
, 2010 The research measures on the service quality assessment in three research samples of tax-collecting government agencies by using customer as the respondents.
Ali, Noor Azman +2 more
core
Muslim Travellers’ Perception on Quality of Service by Umrah and Hajj Travel Agencies in Malaysia
, 2019 Millions of Muslims from all over the world perform Umrah and Hajj every year. There were 250,000 pilgrims from Malaysia in 2017, and the number is expected to grow by 20 percent in 2018.
Azizul Yadi Yaakop +2 more
core +1 more source