Results 51 to 60 of about 11,019 (260)
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
This study aimed (1) to analyze the role of research results in the formulation of border management policies in North Central Timor Regency conducted by the Regional Border Management Agency of North Central Timor Regency and (2) to analyze the obstacles faced by the Regional Border Management Agency in applying research results in the process of the ...
Yohanes Fritantus, Makarius Erwin Bria
openaire +3 more sources
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
A set of finance management regulations suitable for interior agencies’ use should be formulated to ensure the financial secure operation among project interior agencies upon implementing donor’ s projects.In this article,in line with the properties of ...
DU Qing, HE Lin, XIE Yan-fang
doaj
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
LABOR RESOURCES AND LABOR UTILIZATION IN VINH CITY, NGHE AN PROVINCE IN THE PERIOD 2012-2022
Labour resources and employment are top concerns in the socio-economic development strategies of every country and locality on the path of development. This article analyses and clarifies the current state of labour resources and employment in Vinh City
Phan Thi Van
doaj +1 more source
Research to guide management of outdoor recreation and tourism in parks and protected areas
A framework for managing outdoor recreation and tourism in parks and protected areas was presented in this article. This management-by-objectives framework includes, (1) formulating indicators and standards of quality, (2) monitoring indicators of ...
Robert E. Manning
doaj +1 more source
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Research progress on evaluation index system of nursing quality in nursing homes
This paper introduced the research on the evaluation index system of nursing quality in nursing home institutions at home and abroad,analyzed the problems in the quality of nursing services in pension agencies in China,and aiming to draw lessons from ...
王春霞, 纪代红, 李亮
doaj

