Results 71 to 80 of about 40,199 (294)

PERANCANGAN DAN PEMBUATAN APLIKASI SISTEM PAKAR UNTUK DIAGNOSA AWAL GANGGUAN PADA TRAFO ARUS [PDF]

open access: yes, 2013
Tujuan dari penelitian ini adalah membuat suatu program sistem pakar yang berisi pengetahuan dari seorang pakar yang diyakini kebenarannya yang memiliki kemampuan untuk dapat mendiagnosa gangguan yang sering terjadi pada trafo arus secara cepat dan tepat
Ismail, Taufik
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Plane geometry theorem proving using forward chaining [PDF]

open access: yesArtificial Intelligence, 1975
A computer program is described which operates on a subset of plane geometry. Its performance not only compares favorably with previous computer programs, but within its limited problem domain (e.g., no curved lines nor introduction of new points), it also invites comparison with the best human theorem provers.
openaire   +3 more sources

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Expert System for Diagnosing Diseases in Rubber Plants using the Forward Chaining and Dampster Shafer Methods

open access: yesSistemasi: Jurnal Sistem Informasi
Rubber plants are important crops in various countries. Rubber plants have many benefits for human life. Rubber plant diseases cause many losses to farmers.
Indri Ayu Ningrum   +2 more
doaj   +1 more source

Expert System for Diagnosis of Plant Pest and Disease Horticulture with Forward and Backward Chaining Inference

open access: yesJurnal Teknologi dan Sistem Komputer, 2017
One of the obstacles to doing cultivation of horticulture plant is to overcome pest and disease. Pest and disease attack can decrease productivity and even causes harvest fail that influence toward one of income sources in the country.
Ginanjar Wiro Sasmito
doaj   +1 more source

Data-driven backward chaining [PDF]

open access: yes
The C Language Integrated Production System (CLIPS) cannot effectively perform sound and complete logical inference in most real-world contexts. The problem facing CLIPS is its lack of goal generation.
Haley, Paul
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

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