Results 31 to 40 of about 1,333,112 (303)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Metaphor forces argument overtness

open access: yesLinguistics
This paper uncovers how metaphor forces argument overtness – across languages and parts of speech. It addresses the relationship between semantically unsaturated terms, functors, and the argument terms that complete them.
Reinöhl Uta, Ellison T. Mark
doaj   +1 more source

A method for calculating loss of shale gas during coring based on forward modeling

open access: yesEnergy Science & Engineering, 2021
The loss of shale gas from conventional wells during coring directly affects the accuracy of measurement of shale gas content and the efficient development and utilization of shale gas.
Junbo He   +5 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

BIM technology of implicit and explicit parts of historical building components based on point cloud data and digital radiographic image: a review

open access: yesJournal of Asian Architecture and Building Engineering
This paper reviews the modeling methods of the explicit and implicit parts of historical building components, including forward modeling and reverse modeling, with a focus on sorting out the rapid modeling methods for special-shaped components and ...
Jun Cai   +5 more
doaj   +1 more source

Modeling Breast Ultrasound on the Applicability of Commonly Made Approximations

open access: yesArchives of Acoustics, 2018
To design breast ultrasound scanning systems or to test new imaging methods, various computer models are used to simulate the acoustic wave field propagation through a breast. The computer models vary in complexity depending on the applied approximations.
Ulas TASKIN   +3 more
doaj   +1 more source

Deep Markov Random Field for Image Modeling

open access: yes, 2016
Markov Random Fields (MRFs), a formulation widely used in generative image modeling, have long been plagued by the lack of expressive power. This issue is primarily due to the fact that conventional MRFs formulations tend to use simplistic factors to ...
A Dempster   +20 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Numerical method for solving multipoints elliptic-parabolic equation for dehydration process [PDF]

open access: yes, 2012
Drying is the oldest and efficient form of preserving fruits. This research focuses on the mathematical modeling of tropical fruits dehydration using instant controlled pressure drop (Détente Instantanée Controlée or known as DIC) technique.
Alias, Norma   +2 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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