Results 31 to 40 of about 264,379 (313)

Forward models and passive psychotic symptoms [PDF]

open access: yesFrontiers in Human Neuroscience, 2015
Pickering and Clark (2014) present two ways of viewing the role of forward models in human cognition: the auxiliary forward model (AFM) account and the integral forward model (IFM) account. The AFM account “assumes a dedicated prediction mechanism implemented by additional circuitry distinct from the core mechanisms of perception and action” (p.
openaire   +4 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Metaphor forces argument overtness

open access: yesLinguistics
This paper uncovers how metaphor forces argument overtness – across languages and parts of speech. It addresses the relationship between semantically unsaturated terms, functors, and the argument terms that complete them.
Reinöhl Uta, Ellison T. Mark
doaj   +1 more source

A method for calculating loss of shale gas during coring based on forward modeling

open access: yesEnergy Science & Engineering, 2021
The loss of shale gas from conventional wells during coring directly affects the accuracy of measurement of shale gas content and the efficient development and utilization of shale gas.
Junbo He   +5 more
doaj   +1 more source

Generalized Monotone Incremental Forward Stagewise Method for Modeling Count Data: Application Predicting Micronuclei Frequency

open access: yes, 2015
The cytokinesis-block micronucleus (CBMN) assay can be used to quantify micronucleus (MN) formation, the outcome measured being MN frequency. MN frequency has been shown to be both an accurate measure of chromosomal instability/DNA damage and a risk ...
Makowski, Mateusz   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

BIM technology of implicit and explicit parts of historical building components based on point cloud data and digital radiographic image: a review

open access: yesJournal of Asian Architecture and Building Engineering
This paper reviews the modeling methods of the explicit and implicit parts of historical building components, including forward modeling and reverse modeling, with a focus on sorting out the rapid modeling methods for special-shaped components and ...
Jun Cai   +5 more
doaj   +1 more source

Modeling Breast Ultrasound on the Applicability of Commonly Made Approximations

open access: yesArchives of Acoustics, 2018
To design breast ultrasound scanning systems or to test new imaging methods, various computer models are used to simulate the acoustic wave field propagation through a breast. The computer models vary in complexity depending on the applied approximations.
Ulas TASKIN   +3 more
doaj   +1 more source

Seasonality in cocoa spot and forward markets: empirical evidence

open access: yes, 2012
This paper first describes the main features of supply and demand in cocoa spot markets. A state- variable model is proposed to describe the random evolution of cocoa forward curves over time, which essentially adapts to agricultural commodities ...
Geman, Hélyette, Sarfo, S.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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