Results 71 to 80 of about 15,708 (271)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Ecoefficient Timber Forwarding Based on Nominal Ground Pressure Analysis
Croatian Journal of Forest Engineering, 2011 This paper presents the research of possibilities of forwarding timber in an efficient and environmentally friendly way, under conditions of limited bearing capacity of gley soils of Croatian lowland forests due to their increased moisture all the year ...
Tomislav Poršinsky +2 more
doaj
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Ciência e AgrotecnologiaPlanted forests occupy more than 6.5 million ha in Brazil, where harvest and logging operations are performed with increasingly heavier machinery, increasing the risk of soil compaction. Soil compaction can be avoided if soil load bearing capacity is not
Maria Luiza de Carvalho Andrade +5 more
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Application of harvester technologies of timber logging in the process-oriented environment
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2009 Harvester technologies of timber logging currently represent the high spot of technologies used in forestry for timber harvesting and forwarding. A typical feature of the “harvester– forwarder” combination is production rate, which is many times higher ...
Pavel Máchal, Luboš Bartoš
doaj +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Vehicle density based multihop broadcast protocol in VANET
Tongxin xuebao, 2016 In vehicular ad hoc networks (VANET), the medium access control (MAC) protocol was of crucial importance to provide time-critical multihop broadcast. Contemporary multihop broadcast protocols in VANET usually choose the farthest node in broadcast range ...
Jia-wei HUANG +3 more
doaj +2 more sources