Results 51 to 60 of about 1,021 (260)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Integrated Forward-Forward Algorithm: Integrating Forward-Forward and Shallow Backpropagation With Local Losses

open access: yesCoRR, 2023
The backpropagation algorithm, despite its widespread use in neural network learning, may not accurately emulate the human cortex's learning process. Alternative strategies, such as the Forward-Forward Algorithm (FFA), offer a closer match to the human cortex's learning characteristics.
openaire   +2 more sources

Ecoefficient Timber Forwarding Based on Nominal Ground Pressure Analysis

open access: yesCroatian Journal of Forest Engineering, 2011
This paper presents the research of possibilities of forwarding timber in an efficient and environmentally friendly way, under conditions of limited bearing capacity of gley soils of Croatian lowland forests due to their increased moisture all the year ...
Tomislav Poršinsky   +2 more
doaj  

Alterações do solo influenciadas pelo tráfego e carga de um "forwarder" nas entrelinhas de uma floresta de eucalipto Soil disturbances as affected by load and traffic intensity of a forwarder along interrows of a eucalypt stand

open access: yesRevista Brasileira de Ciência do Solo, 2007
Durante a retirada de madeira de povoamentos florestais as máquinas trafegam numa mesma linha várias vezes, o que pode causar a compactação do solo.
Sérgio Ricardo Silva   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Finding the Forward-Douglas–Rachford-Forward Method [PDF]

open access: yesJournal of Optimization Theory and Applications, 2019
We consider the monotone inclusion problem with a sum of 3 operators, in which 2 are monotone and 1 is monotone-Lipschitz. The classical Douglas--Rachford and Forward-backward-forward methods respectively solve the monotone inclusion problem with a sum of 2 monotone operators and a sum of 1 monotone and 1 monotone-Lipschitz operators.
Ernest K. Ryu, Bang Công Vu
openaire   +2 more sources

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Magnitude of WBV Affecting the Tractor with a Timber Trailer Operator During Individual Timber Forwarding Operations

open access: yesSouth-East European Forestry
The study deals with measuring operator’s whole-body vibrations (WBV) at work with the tractor with a timber trailer. The research was done directly at the workplace during the production stage of timber forwarding.
David Sláma   +2 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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