Results 71 to 80 of about 1,018 (260)

Alterações do solo influenciadas pelo tráfego e carga de um "forwarder" nas entrelinhas de uma floresta de eucalipto Soil disturbances as affected by load and traffic intensity of a forwarder along interrows of a eucalypt stand

Revista Brasileira de Ciência do Solo, 2007
Durante a retirada de madeira de povoamentos florestais as máquinas trafegam numa mesma linha várias vezes, o que pode causar a compactação do solo.
Sérgio Ricardo Silva, Nairam Félix de Barros, Liovando Marciano da Costa, Eduardo de Sá Mendonça, Fernando Palha Leite   +4 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Self-Contrastive Forward-Forward algorithm

Nature Communications
Agents that operate autonomously benefit from lifelong learning capabilities. However, compatible training algorithms must comply with the decentralized nature of these systems, which imposes constraints on both the parameter counts and the computational resources. The Forward-Forward (FF) algorithm is one of these.
Xing Chen, Dongshu Liu, Jérémie Laydevant, Julie Grollier   +3 more
openaire   +3 more sources

PROBLEM OF COMMON TRANSPORT SYSTEM ORGANIZATION

Современные информационные технологии и IT-образование, 2018
The paper discusses the problem of common transport system creation from system-wide positions. Much attention is focused on two aspects – active self-maintenance in the environment with disorganization and dual nature of an organized object – as a ...
Pyotr A. Kozlov, Nikolay A. Tushin, Vitaliy S. Kolokolnikov   +2 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Productivity of a John Deere Harvester Unit in Deciduous Stands

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2014
The aim of the presented paper was to determine the productivity of a John Deere 1070D harvester in deciduous coppices of Quercus petraea and Fagus sylvatica, in thinnings over 50 years of age.
Jozef Slugeň, Pavel Peniaško, Valéria Messingerová, Martin Jankovský   +3 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Distance driven and driving speed when forwarding during final felling in Central Sweden

Journal of Forest Science, 2019
Factors affecting forwarding work are interesting because they can be used to better optimize forwarding routes and to predict costs. The main objective of this study was to investigate the association between driving speed and driving distance when ...
Simon Berg, Back Tomas Ersson, Jussi Manner   +2 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Possibilities of using price analysis in decision making on the use of harvester technology in forestry

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2009
The concept of harvester technology is understood as a fully mechanized harvesting technology for the purpose of timber logging, which means timber handling, extraction and forwarding or skidding.
Luboš Bartoš, Pavel Máchal, Alois Skoupý   +2 more
doaj   +1 more source