Results 61 to 70 of about 19,224 (263)

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Software-Defined Named Data Networking in Literature: A Review

open access: yesFuture Internet
This paper presents an in-depth review of software-defined named data networking (SD-NDN), a transformative approach in network architectures poised to deliver substantial benefits.
Albatool Alhawas, Abdelfettah Belghith
doaj   +1 more source

Blockchain Potential in Tilapia Supply Chain in Ghana

open access: yesActa Technica Jaurinensis, 2018
In a country like Ghana where Tilapia is the most preferred and cheapest source of animal protein, closer attention must be paid to the supply chain of such a product.
Abderahman Rejeb
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Soil Compaction Induced by Three Timber Extraction Options: A Controlled Experiment on Penetration Resistance on Silty-Loamy Soils

open access: yesApplied Sciences
Local effects of ground-based timber harvesting, such as soil compaction, are often important for forest management and resilience of forests. One way to evaluate the compaction of the forest soils is by the penetration resistance.
Mădălina Florina Presecan   +2 more
doaj   +1 more source

The impact of leadership styles on innovation - a review

open access: yesJournal of Innovation Management, 2016
This paper reviews the insights that research offers on the impact of different leadership styles on innovation. To do so, we develop a framework, structuring research insights into four dimensions: people, means, effects, and goals/outcomes for ...
Peter Kesting   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

INF-NDN IoT: An Intelligent Naming and Forwarding in Name Data Networking for Internet of Things

open access: yesIEEE Access
Internet of things (IoT) has emerged as a quintessential paradigm of communication systems. Current literature introduces notion of a named data network for IoT (NDN-IoT), optimizing IoT communication by employing name-based networking.
Ghulam Musa Raza   +4 more
doaj   +1 more source

Halal Meat Supply Chain Traceability based on HACCP, Blockchain and Internet of Things

open access: yesActa Technica Jaurinensis, 2018
Recently, Halal food has drawn remarkable attention of many consumers around the world. Besides to being unsafe, Halal food such as meat can encounter several issues throughout its supply chain and logistics.
Abderahman Rejeb
doaj   +1 more source

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