Results 61 to 70 of about 199,692 (338)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
On Advancements of the Forward-Forward Algorithm [PDF]
2025 11th International Conference on Control, Decision and Information Technologies (CoDIT)The Forward-Forward algorithm has evolved in machine learning research, tackling more complex tasks that mimic real-life applications. In the last years, it has been improved by several techniques to perform better than its original version, handling a challenging dataset like CIFAR10 without losing its flexibility and low memory usage.
Ortiz Torres, Mauricio +2 more
openaire +5 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Forward–forward training of an optical neural network
Optics Letters, 2023 Neural networks (NNs) have demonstrated remarkable capabilities in various tasks, but their computation-intensive nature demands faster and more energy-efficient hardware implementations. Optics-based platforms, using technologies such as silicon photonics and spatial light modulators, offer promising avenues for achieving this goal.
Ilker Oguz +8 more
openaire +3 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Averaged vibration levels during courier parcel delivery service in small truck in Hungary [PDF]
FME Transactions, 2018 In recent years there continues to be an increase in courier parcel delivery services due to the growing global online economy and express parcel shipments.
Böröcz Péter
doaj
Conception of a Malicious Node Detection System for Tactical Wireless Sensor Networks [PDF]
Problemy MechatronikiThis article presents the motivation and outlines a concept for mechanisms supporting data packet routing and exchange in tactical wireless sensor networks.
Wiesław JABŁOŃSKI (wieslaw.jablonski@interia.pl) +1 more
doaj +1 more source
Modeling transportation routes of the pick-up system using location problem: a case study
Open Engineering, 2020 In today’s increasingly globalizing world, the demand for the transport of more and more specific kinds of goods is constantly growing. Greater diversity of the objects of transport extends the range of consignees and consignors, which implies the ...
Stopka Ondrej +3 more
doaj +1 more source
A Light-Weight Forwarding Plane for Content-Centric Networks
, 2016 We present CCN-DART, a more efficient forwarding approach for content-centric networking (CCN) than named data networking (NDN) that substitutes Pending Interest Tables (PIT) with Data Answer Routing Tables (DART) and uses a novel approach to eliminate ...
Garcia-Luna-Aceves, J. J. +1 more
core +1 more source