Results 111 to 120 of about 33,521 (167)

Lgr5 deficiency accelerates intervertebral disc degeneration via NF-κB activation and enhanced osteoclastogenesis. [PDF]

Front Med (Lausanne)
Che F, Zhao Q, Wang J, Huang G, Yu L, Li G, Xu L, Wang D.   +7 more
europepmc   +1 more source

Optimal Transmission Performance of Quadrature Wireless Resonators at 3 T

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To demonstrate a method for optimizing the efficiency of wireless resonators using tailored excitation from a dual‐transmit birdcage coil (BC), and to present the design and experimental investigation of a quadrature resonator for 3 T breast MRI application.
Leila Sharipova, Dmitrii Tikhonenko, Christophe Vilmen, David Bendahan, Stefan Enoch, Redha Abdeddaim, Alena Shchelokova, Marc Dubois   +7 more
wiley   +1 more source

RSM-optimized co-encapsulation of Lactobacillus brevis LSe and FOS in calcium alginate: enhancing encapsulation efficiency and bacterial growth. [PDF]

BMC Microbiol
Abolhassanzadeh-Mahani S, Talebian A, Ameri A, Shakibaie M, Abadi B, Adeli-Sardou M, Ameri A, Forootanfar H.   +7 more
europepmc   +1 more source

Early Growth Response 1‐Associated Epithelial Autophagy‐Related Changes in Allergic Airway Inflammation

Pediatric Discovery, EarlyView.
House dust mite (HDM) exposure induces early growth response 1 (EGR1) expression in airway epithelial cells and is accompanied by autophagy‐associated alterations, including increased LC3B‐II and Vps34 levels and decreased p62 abundance. Manipulation of EGR1 expression modulates these autophagy‐related changes, whereas pharmacological inhibition of ...
Xinyang Wang, Jie Ren, Yan Zhao, Zhengxiu Luo   +3 more
wiley   +1 more source

FOS drives podocyte injury and renal fibrosis in diabetic kidney disease via direct Smad3 binding. [PDF]

Cell Mol Life Sci
Sun M, Yan T, Zhao W, Cheng Z.
europepmc   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Conjugated Linoleic Acid Alleviates Hepatic Steatosis and Liver Damage in Estradiol-Induced FLHS Roosters by Reshaping Lipid Metabolism and Inhibiting the MAPK/NF-κB-Mediated Inflammation Cascade. [PDF]

Animals (Basel)
Liu X, Zhang H, Gao Q, Shang Y, Shi T, Yan P, Fu C.   +6 more
europepmc   +1 more source

A Multiple‐Model‐Informed Drug‐Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 572-582, March 2025.
ABSTRACT The antitumor efficacy of an intratumoral injection of a genetically engineered oncolytic vaccinia virus carrying human IL‐7 and murine IL‐12 genes (hIL‐7/mIL‐12‐VV) was demonstrated in CT26.WT‐bearing mice. In the CT26.WT‐bearing mouse model, the efficacy of the combination of hIL‐7/mIL‐12‐VV plus the anti‐programmed cell death protein (PD)‐1
Akihiro Yamada, Mary P. Choules, Frances A. Brightman, Shigeru Takeshita, Shinsuke Nakao, Nobuaki Amino, Takeshi Nakayama, Masato Takeuchi, Kanji Komatsu, Fernando Ortega, Hitesh Mistry, David Orrell, Christophe Chassagnole, Peter L. Bonate   +13 more
wiley   +1 more source