Overcoming the drug resistance barrier: progress in fosfomycin combination therapy against multidrug-resistant pathogens. [PDF]
Wu Y +5 more
europepmc +1 more source
The Oral‐Gut Axis: Bidirectional Interactions Between Microbiome and Diseases
This study aims to summarize the mechanisms underlying ectopic colonization of the gut by oral pathobionts and the microbial and host factors that regulate this process. ABSTRACT Increased colonization of typically oral microorganisms is frequently observed in the gut mucosa or lumen of individuals with gastrointestinal disorders, including patients ...
Shinya Ebihara, Nobuhiko Kamada
wiley +1 more source
A stress-responsive neurovascular axis shapes skin immune accessibility. [PDF]
Yu Y +9 more
europepmc +1 more source
Anhydrous minerals in asteroid Bennu: Evidence for well‐preserved primordial components
Abstract Aqueously altered carbonaceous astromaterials are dominated by secondary minerals, but a minor fraction of primary, anhydrous silicates and oxides escape alteration, offering insight into the original composition of asteroid parent bodies. We report the mineralogy, petrology, mineral chemistry, and oxygen isotopes of anhydrous minerals—50 ...
S. S. Russell +23 more
wiley +1 more source
Prebiotics and Gut Health: Mechanisms, Clinical Evidence, and Future Directions. [PDF]
Monteiro CRAV +7 more
europepmc +1 more source
Transcriptional profiling of the primary cell envelope stress response (CESR) of Bacillus subtilis exposed to a range of cell wall‐targeting antimicrobials, combining RNAseq and high‐resolution tiling arrays. We revealed the complexity of the CESR, the contribution of extracytoplasmic function sigma factors (ECFs) and two‐component signal transduction ...
Qian Zhang +12 more
wiley +1 more source
Exploration of the aromatic abietane diterpenoid scaffold in the development of ArnT-mediated colistin resistance inhibitors. [PDF]
Cammarone S +12 more
europepmc +1 more source
Three closely linked X‐chromosomal genes potentially control sex determination in Cannabis sativa
Summary Sex determination mechanisms in dioecious plants remain poorly understood yet offer an excellent model system to study genetic changes underlying morphological evolution. We investigated the genetic basis of sex determination in Cannabis sativa, combining quantitative trait locus mapping in a segregating population, comparative transcriptomics ...
Matteo Toscani +8 more
wiley +1 more source
Protocol for whole-tissue immunolabeling, optical clearing, and lightsheet imaging of c-Fos protein expression in unsectioned mouse brains. [PDF]
Fu K, Yang J.
europepmc +1 more source
Inflammation and mechanical force‐induced bone remodeling
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon +6 more
wiley +1 more source

