Results 161 to 170 of about 155,411 (214)

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

Advanced Science, Volume 13, Issue 19, 2 April 2026.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin, Si‐ying He, Ting‐hui Xiao, Da‐mao Dai, Xin‐jia Hu, Nan Jiang   +5 more
wiley   +1 more source

Ebselen Suppresses Breast Cancer Tumorigenesis by Inhibiting YTHDF1-Mediated c-Fos Expression. [PDF]

Int J Mol Sci
Vasukutty A, Bhattarai PY, Choi HS.
europepmc   +1 more source

Structural Aspects of Lithium‐Ion Conduction in the Phosphidotitanate Li8TiP4 and Its Comparison With Li7+5xTa1−xP4 and Li8−xTi1−xTaxP4

Chemistry – A European Journal, Volume 32, Issue 13, 1 April 2026.
ABSTRACT The chemical system Li/Ti/P has previously been subject to intensive investigation. However, reliable structural data for the reported phases have remained elusive. Motivated by the growing interest in phosphorus‐based lithium‐ion conductors, we have reinvestigated the synthesis, crystal structure, and physical properties of Li8TiP4.
David Müller, Tobias Kutsch, Sabine Zeitz, Viktor Hlukhyy, Gabriele Raudaschl‐Sieber, Wilhelm Klein, Thomas F. Fässler   +6 more
wiley   +1 more source

Alteration of BDNF and noradrenergic markers in locus coeruleus in a mouse model of cancer-induced bone pain. [PDF]

PLoS One
Yuan M, Zhang L, Zhu H, Xie M.
europepmc   +1 more source

Targeting Ferroptosis Pathways for Synaptic Protection in Sevoflurane‐Induced Cognitive Impairment: A Nanomedicine Approach

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
Sevoflurane exposure triggers iron‐dependent lipid peroxidation and ferroptosis, leading to synaptic damage and cognitive dysfunction. Targeted nanodelivery systems that cross the blood–brain barrier can precisely modulate ferroptotic pathways, reduce oxidative injury, and rescue synaptic integrity, offering a promising strategy for preventing ...
Bin Zhao, Changming Wang, Mingming Zhang
wiley   +1 more source

Dietary Fiber Regulation of Gut Microbiota and Bile Acid Metabolism in Animals: Implications for Animal Nutrition. [PDF]

Vet Sci
Lai J, Zentek J, Grześkowiak ŁM.
europepmc   +1 more source

Pre‐, Pro‐, Post‐, and Synbiotics for Skin Health: A Narrative Review of Cosmetic and Dermatological Applications

Dermatological Reviews, Volume 7, Issue 2, April 2026.
ABSTRACT Background Prebiotics, probiotics, postbiotics, and synbiotics have been increasingly investigated and incorporated into cosmetic formulations to preserve or restore skin health, function, and esthetics. Objective To review biotics applications in cosmetology, discussing their concepts, general characteristics, and potential benefits and ...
Guilherme Carvalho Tavares da Silva, Kátia de Pádua Silva, Ana Carolina Furian da Silva, Larissa Pavanello, Gabriela de Moraes Saqui, Andréa Fernandes Eloy Costa da França, Gislaine Ricci Leonardi, Karina Cogo‐Müller   +7 more
wiley   +1 more source

Bifidobacterium longum and prebiotic interventions restore early-life high-fat/high-sugar diet-induced alterations in feeding behavior in adult mice. [PDF]

Nat Commun
Cuesta-Marti C, Ponce-España E, Uhlig F, Stoltenborg I, Wasiewska LA, Kareem L, Hedayatpour D, Olavarría-Ramírez L, Rosell-Cardona C, Bastiaanssen TFS, Tofani GSS, Valderrama B, Vlckova K, Dickson SL, Lavelle A, Stanton C, Ross RP, Cryan JF, Dinan TG, Clarke G, O'Mahony SM, Schellekens H.   +21 more
europepmc   +1 more source