Results 131 to 140 of about 39,429 (167)

Gut microbiota‐targeted interventions for depression in adolescents and young adults: Mechanisms, evidence strength and clinical strategies—A narrative review

General Psychiatry, Volume 39, Issue 4, August 2026.
ABSTRACT Depression in adolescents and young adults is common, associated with substantial functional impairment and characterised by limited treatment efficacy. The microbiota–gut–brain (MGB) axis has emerged as a potential therapeutic target for depression.
Hanchen Hou, Yinan Li, Wanting Tang, Yiwen Gao, Yuanyuan Tian, Fei Chen, Lige Zhang, Jushuang Zhang, Xiaoxia Xu, Yao Li, Yi Li, Qingshan Wang, Lingli Liu, Teng Teng, Hao Wu, Xinyu Zhou   +15 more
wiley   +1 more source

The Hypnotic Effect of Spinosin Is Mediated by Adenosine A_2A Receptors in Male Mice. [PDF]

Nutrients
Zhang J, Zhang H, Zhao W, Li L, Chu L.
europepmc   +1 more source

Imeglimin Attenuates Skeletal Muscle Atrophy in Mouse Models of Obesity and Ageing

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Sarcopenia is a major contributor to frailty and mortality in ageing and obesity and is tightly linked to metabolic dysfunction. Imeglimin is a first‐in‐class oral hypoglycaemic agent targeting mitochondrial function; however, despite the central role of mitochondria in skeletal muscle homeostasis, its effects on skeletal muscle ...
Yangli Ye, Diandian Qian, Ikumi Nomura, Naoki Kobayashi, Yukiko Shimizu, Tadashi Okamura, Motoharu Awazawa, Kohjiro Ueki   +7 more
wiley   +1 more source

Subgroup of meningiomas involving FOS and FOSB gene fusions. [PDF]

Nat Commun
Yalcin K, Alanya H, Gultekin B, Samper Figuera D, Barak T, Miyagishima DF, Youngblood MW, Hjerthen MG, Brooks A, Samuel Lopez N, O'Brien J, Chavez MM, Dincer A, Wu H, Omay SB, Yasuno K, Bilguvar K, Ercan-Sencicek AG, Mishra-Gorur K, McGuone D, Moliterno J, Gunel M, Erson-Omay EZ.   +22 more
europepmc   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source

A GABAergic neural circuit from the suprachiasmatic nucleus to DG drives cognitive impairment in migraine mice. [PDF]

J Headache Pain
Xie Q, Zhang Y, Huang Y, Yan W, Zhou Y, Xiao Z.   +5 more
europepmc   +1 more source

Improved Radiofrequency Safety Modelling in MRI Using In Vivo Measurements of Brain Conductivity

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
A workflow for the comparison of simulated and measured B1+$$ {B}_1^{+} $$ maps was developed and applied to a study on human tissue (brain) electrical conductivity, investigating differences between conductivity values from ex vivo and in vivo measurements.
Guillaume Paillart, Zhongzheng He, Grecia Romero, Pauline Ferry, Khalid Ambarki, Paul Soullié, Jacques Felblinger, Freddy Odille   +7 more
wiley   +1 more source

The basal forebrain-DMN/solv cholinergic projection mediates the attenuation of brain injury after cardiopulmonary resuscitation. [PDF]

World J Emerg Med
Xia S, Chen Z, He Y, Yang Y, Qin M, Xu L, Peng H, Liu H, Qiu S, Liu L.   +9 more
europepmc   +1 more source

Current state of neonatal intestinal rehabilitation care in North America: A descriptive survey‐based study

Nutrition in Clinical Practice, Volume 41, Issue 4, Page 1180-1190, August 2026.
Abstract Background Multidisciplinary care under intestinal rehabilitation programs (IRPs) improves survival in pediatric intestinal failure (IF). Professional societies recommend the management of pediatric patients with IF by an IRP. Whether these recommendations are followed in cases of neonatal IF is currently unclear.
Katie A. Huff, Ethan A. Mezoff, Abeer Azzuqa, Darren Bodkin, Hannah Hightower, Mark R. Corkins, Jeffery A. Rudolph, Katie M. Strobel, Jae H. Kim, Muralidhar H. Premkumar, Sujir Pritha Nayak, the Children's Hospitals Neonatal Consortium Intestinal Failure Focus Group   +11 more
wiley   +1 more source

Quercetin improves retinal glycolysis to slow myopia progression through orchestrating the AKT/FOXO/HK2 axis. [PDF]

Redox Biol
Zhang R, Zhang M, Xie Y, Wei H, Yang Z, Wen Y, Hao J, Du Y, Yang Y, Yin X, Zhang Y, Jiang W, Bi H, Guo D.   +13 more
europepmc   +1 more source