Results 21 to 30 of about 536,475 (113)

Machine Learning Identifies Pan-Cancer Landscape of Nrf2 Oxidative Stress Response Pathway-Related Genes

Oxidative Medicine and Cellular Longevity, 2022
Background. Oxidative stress produced a large amount of reactive oxygen species (ROS), which played a pivotal role in balanced ability and determining cell fate.
Na Li, X. Zhan
semanticscholar   +1 more source

Exogenous IFN-beta regulates the RANKL-c-Fos-IFN-beta signaling pathway in the collagen antibody-induced arthritis model

Journal of Translational Medicine, 2014
BackgroundAlthough a variety of drugs have been used to treat the symptoms of rheumatoid arthritis (RA), none of them are able to cure the disease.
Rong Zhao, N. Chen, Xiao-Wei Zhou, Ping Miao, Chaoying Hu, L. Qian, Qi-wen Yu, Ji-ying Zhang, H. Nie, Xue-hua Chen, Pu Li, R. Xu, L. Xiao, Xin Zhang, Jian-Ren Liu, Dong-qing Zhang   +15 more
semanticscholar   +2 more sources

Renoprotective Effect of Agalsidase Alfa: A Long-Term Follow-Up of Patients with Fabry Disease

Journal of Clinical Medicine, 2022
Fabry disease is a rare lysosomal storage disorder caused by mutations in the GLA gene, which, without treatment, can cause significant renal dysfunction.
M. Cybulla, K. Nicholls, S. Feriozzi, A. Linhart, J. Torras, B. Vujkovac, J. Botha, C. Anagnostopoulou, M. West   +8 more
semanticscholar   +1 more source

Identification of New Molecular Biomarkers in Ovarian Cancer Using the Gene Expression Profile

Journal of Clinical Medicine, 2022
Ovarian cancer is a common cause of death among women worldwide. The current diagnostic and prognostic procedures available for the treatment of ovarian cancer are either not specific or are very expensive.
P. Olbromski, Piotr Pawlik, A. Bogacz, S. Sajdak   +3 more
semanticscholar   +1 more source

Environmental Enrichment Components Required to Reduce Methamphetamine-Induced Behavioral Sensitization in Mice: Examination of Behaviors and Neural Substrates

Journal of Clinical Medicine, 2022
Environmental enrichment (EE) involves the presentation of various sensory, physical, social, and cognitive stimuli in order to alter neural activity in specific brain areas, which can ameliorate methamphetamine (MAMPH)-induced behavioral sensitization ...
Cai-N Cheng, Shaw-Jye Wu, A. Huang
semanticscholar   +1 more source

EGFR is required for FOS‐dependent bone tumor development via RSK2/CREB signaling

EMBO Molecular Medicine, 2018
Osteosarcoma (OS) is a rare tumor of the bone occurring mainly in young adults accounting for 5% of all childhood cancers. Because of the limited therapeutic options, there has been no survival improvement for OS patients in the past 40 years.
Markus Linder, E. Glitzner, S. Srivatsa, L. Bakiri, K. Matsuoka, P. Shahrouzi, M. Dumanic, Philipp Novoszel, T. Mohr, O. Langer, T. Wanek, M. Mitterhauser, E. Wagner, M. Sibilia   +13 more
semanticscholar   +1 more source

Curcumin inhibits osteoclastogenic potential in PBMCs from rheumatoid arthritis patients via the suppression of MAPK/RANK/c-Fos/NFATc1 signaling pathways

Molecular Medicine Reports, 2016
The aim of the present study was to determine the effects of curcumin on the osteoclastogenic potential of peripheral blood mononuclear cells (PBMCs) obtained from patients with rheumatoid arthritis (RA), and to investigate the underlying molecular ...
W. Shang, Ling-jie Zhao, Xiao-lei Dong, Zhi-ming Zhao, Jing Li, Beibei Zhang, Hui Cai   +6 more
semanticscholar   +1 more source

Overexpression of c-fos promotes cell invasion and migration via CD44 pathway in oral squamous cell carcinoma.

Journal of Oral Pathology & Medicine, 2015
BACKGROUND Oral squamous cell carcinoma (OSCC) is one of the most deadly malignant tumors with high invasive potential and frequently cervical lymph node metastasis.
C. Dong, D. Ye, Wen-Bin Zhang, H. Pan, Zhi-Yuan Zhang, Lei Zhang   +5 more
semanticscholar   +1 more source

The Paradoxical Effect Hypothesis of Abused Drugs in a Rat Model of Chronic Morphine Administration

Journal of Clinical Medicine, 2021
A growing body of studies has recently shown that abused drugs could simultaneously induce the paradoxical effect in reward and aversion to influence drug addiction.
Y. Yu, A. He, M. Liou, C. Ou, A. Kozłowska, Pingwen Chen, A. Huang   +6 more
semanticscholar   +1 more source

Expression levels of transcription factors c-Fos and c-Jun and transmembrane protein HAb18G/CD147 in urothelial carcinoma of the bladder

Molecular Medicine Reports, 2017
The aim of the present study was to investigate the prognostic significance of the expression of transcription factors, c-Fos, c-Jun and transmembrane protein CD147, in urothelial carcinoma of the bladder (UCB).
Muren Huhe, shuangshuang liu, Yang Zhang, Zheng Zhang, Zhi-Nan Chen   +4 more
semanticscholar   +1 more source