Results 31 to 40 of about 536,475 (113)

Screening and verification of potential gene targets in esophageal carcinoma by bioinformatics analysis and immunohistochemistry

Annals of Translational Medicine, 2021
Background To evaluate the potential of candidate proteins as diagnostic markers or drug targets in esophageal carcinoma (ESCA). Methods GSE20347, GSE17351, and GSE45670 were downloaded from Gene Expression Omnibus (GEO).
Pingwu Wen, F. Dayyani, R. Tao, Xiongping Zhong   +3 more
semanticscholar   +1 more source

Femoral–Obturator–Sciatic (FOS) Nerve Block as an Anesthetic Triad for Arthroscopic ACL Reconstruction: Is This the Magic Trick We Were Missing?

Journal of Clinical Medicine
Arthroscopic anterior cruciate ligament (ACL) reconstruction with hamstring grafting is a common orthopedic procedure that is associated with moderate-to-severe pain.
Metaxia V. Bareka, M. Ntalouka, Fragkiskos A. Angelis, M. Mermiri, Aikaterini Tsiaka, Michael Hantes, Eleni Arnaoutoglou   +6 more
semanticscholar   +1 more source

Can Foot Orthoses Benefit Symptomatic Runners? Mechanistic and Clinical Insights Through a Scoping Review

Sports Medicine - Open
Running is a widely practiced sport worldwide associated with a host of benefits on cardiovascular, metabolic, musculoskeletal, and mental health, but often leads to musculoskeletal overuse injuries.
Francis Del Duchetto, Cloé Dussault-Picard, Martine Gagnon, Philippe C Dixon, Y. Cherni   +4 more
semanticscholar   +1 more source

Expression of c-Fos and c-Jun in adjacent cervical spinal cord segments following C7 nerve root rhizotomy in rats: Indication of a neural pathway between adjacent cervical spinal cord segments

Experimental and Therapeutic Medicine, 2013
Cervical radiculopathy is a common disease in clinical practice. However, the symptoms are not confined to the affected spinal cord segment indicated by magnetic resonance imaging (MRI) findings.
Hui Li, Qing Li, K. Xie, S. Feng, Pei Wang, Xinlong Ma   +5 more
semanticscholar   +1 more source

Dynamic Importance of Genomic and Clinical Risk for Coronary Artery Disease Over the Life Course

Circulation Genomic and Precision Medicine
BACKGROUND: Earlier identification of high coronary artery disease (CAD) risk individuals may enable more effective prevention strategies. However, existing 10-year risk frameworks are ineffective at earlier identification.
S. Urbut, S. M. Cho, K. Paruchuri, B. Truong, S. Haidermota, G. Peloso, W. Hornsby, A. Philippakis, A. Fahed, P. Natarajan   +9 more
semanticscholar   +1 more source

Prognosis-related autophagy genes in female lung adenocarcinoma

Medicine, 2020
To screen the prognosis-related autophagy genes of female lung adenocarcinoma by the transcriptome data and clinical data from The Cancer Genome Atlas (TCGA) database. In this study, screen meaningful female lung adenocarcinoma differential genes in TCGA,
Zhong-qiang Liu, Koudong Zhang, Zhangyan Zhao, Zhu Qin, Haicheng Tang   +4 more
semanticscholar   +1 more source

Identification of a novel role of IL-13Rα2 in human Glioblastoma multiforme: interleukin-13 mediates signal transduction through AP-1 pathway

Journal of Translational Medicine, 2018
Previously, we have demonstrated that Interleukin 13 receptor alpha 2 (IL-13Rα2) is overexpressed in approximate 78% Glioblastoma multiforme (GBM) samples.
Rukmini Bhardwaj, A. Suzuki, P. Leland, B. Joshi, R. Puri   +4 more
semanticscholar   +1 more source

UNR/CSDE1 Expression Is Critical to Maintain Invasive Phenotype of Colorectal Cancer through Regulation of c-MYC and Epithelial-to-Mesenchymal Transition

Journal of Clinical Medicine, 2019
CSDE1 (cold shock domain containing E1) gene is located upstream of the N-RAS locus, and codes for an RNA-binding protein named Upstream of N-Ras (UNR). In cancer, CSDE1 has been shown to regulate c-Fos, c-Myc, Pten, Rac1, or Vimentin. UNR/CSDE1 has been
J. Martínez-Useros, Nuria García-Carbonero, Weiyao Li, M. Fernández-Aceñero, I. Cristóbal, R. Rincon, M. Rodríguez-Remírez, A. Borrero-Palacios, J. García-Foncillas   +8 more
semanticscholar   +1 more source

Pancreatic cancer biomarker detection by two support vector strategies for recursive feature elimination.

Biomarkers in Medicine, 2019
AIM Pancreatic cancer is one of the worst malignant tumors in prognosis. Therefore, to reduce the mortality rate of pancreatic cancer, early diagnosis and prompt treatment are particularly important.
Yan Wang, Keke Liu, Qin Ma, Yongfei Tan, Wei Du, Yidan Lv, Yuan Tian, Hao Wang   +7 more
semanticscholar   +1 more source

Stat proteins as intracellular regulators of resistance to myocardial injury in the context of cardiac remodeling and targeting for therapy.

Advances in Clinical and Experimental Medicine, 2017
The roles of STAT (signal transducers and activators of transcription) proteins are widely discussed in relation to other agents like IFN-γ that are involved in cardiovascular diseases.
A. Wincewicz, S. Sułkowski
semanticscholar   +1 more source