Results 61 to 70 of about 3,808 (149)
ChemMedChem, EarlyView.Cocktail soaking using single‐crystal X‐ray diffraction allows high‐throughput crystallographic ligand screening against protein targets. However, protein microcrystals are not amenable to this approach. Herein, a workflow integrating cocktail soaking with automated microcrystal electron diffraction to allow rapid ligand screening, structure ...
Jieye Lin +3 more
wiley +1 more source
Vibrational Partition Functions from Bond Order and Populations Relationships
ChemPhysChem, EarlyView.A new computational model is presented that predicts vibrational partition functions using bond orders and populations relationships (QBOP). This model demonstrates that thermochemical energy contributions can be reasonably approximated based on well‐conditioned orbital populations without the need for a costly Hessian calculation.
Barbaro Zulueta, John A. Keith
wiley +1 more source
Assessing the Sustainable Transition in LSPs Industry
Corporate Social Responsibility and Environmental Management, EarlyView.ABSTRACT The growing pressure on logistics service providers (LSPs) to achieve strong sustainability performance highlights the importance of aligning their practices with technological tools to support such endeavour. Given the significant effort required to implement sustainability measures in companies, it is crucial to focus on implementing these ...
Piera Centobelli
wiley +1 more source
Intensification of Ethylene Carbonate Synthesis via Microwave‐Induced Phase‐Change Cycles
ChemSusChem, EarlyView.Microwave‐assisted heating under ambient pressure reflux conditions is applied to intensify the transesterification of ethylene glycol with dimethyl carbonate. The proposed method enhances energy efficiency and product yield compared to conventional heating, enabling lower catalyst loading, reduced process time, and significantly decreased energy ...
Ioannis Papaioannou +5 more
wiley +1 more source
Drug Testing and Analysis, EarlyView.This study is related to the development of a microextraction method for the determination of 56 psychoactive substances in oral fluid. Sample clean‐up is obtained by parallel artificial liquid membrane extraction and analyzed by liquid chromatography–tandem mass spectrometry.
Martina Croce +6 more
wiley +1 more source
European Journal of Inorganic Chemistry, Accepted Article.Coordination polymers of zinc(II) with three readily accessible 3‐(1H‐imidazol‐1‐yl)propanoate ligands are prepared by combining aqueous solutions of the ligands and zinc(II) salts, resulting in a precipitation of the respective coordination polymers.
Katharina Kodolitsch +5 more
wiley +1 more source
Epileptic Disorders, Volume 27, Issue 2, Page 204-218, April 2025.Abstract Objective Temporal lobe epilepsy (TLE) is the most prevalent form of epilepsy. Prior research has indicated the involvement of the nucleus accumbens shell (NAcSh) in the process of epileptogenesis, thereby implying its potential as a therapeutic target for TLE.
Shuaishuai Xue +10 more
wiley +1 more source
Epilepsia Open, EarlyView.Abstract Objective Investigate real‐world outcomes in drug‐resistant epilepsy (DRE) patients treated with cenobamate as adjunctive treatment to other antiseizure medications (ASMs) within the Early Access Programs (EAP) in Germany, France, and the United Kingdom.
Sylvain Rheims +13 more
wiley +1 more source
The RNA Binding Protein Bcas2 is Required for Antibody Class Switch in Activated‐B Cells
Exploration, EarlyView.Bcas2 recruits DHX15 and SRSF7 to form a protein complex for the splicing of CSR‐related mRNA at the 5' ss and 3' ss, generating two mature mRNA isoforms, which are ultimately translated into CSR‐related proteins. These CSR‐related proteins bind to DNA associated with antibodies, affecting the DSB repair of the relevant DNA after AID induction, thereby
Yu Chen +29 more
wiley +1 more source