Results 81 to 90 of about 4,760 (166)

Inhibitory tone in the dentate gyrus dynamically prioritizes memory flexibility or stability by tuning a sensitivity-consistency continuum. [PDF]

PLoS Biol
Pérez-Montoyo E, Caramés JM, Garcia-Hernandez R, Peralta-Cañadas M, Canals S, Marcos E.   +5 more
europepmc   +1 more source

Age‐Associated B Cells Contribute to Inflammation Via Antibody‐Independent Mechanisms in Takayasu Arteritis

Arthritis &Rheumatology, EarlyView.
Objective Although Takayasu arteritis (TAK) is not a prototypical autoantibody‐mediated disease, accumulating evidence suggests that B cells are involved. This study aimed to investigate the pathway of B cell activation and its contributions to TAK pathogenesis. Methods Histologic analysis of paravascular lymph nodes and affected arteries was conducted
Chenglong Fang, Xiaoxi Yang, Xiaochuan Sun, Shangyi Jin, Lihong Du, Jinwei Gao, Jing Li, Zhen Chen, Yuexin Chen, Mengtao Li, Xinping Tian   +10 more
wiley   +1 more source

Application of Enzyme Engineering and Synthetic Biology for Modulated Transformation of Fructooligosaccharides (FOSs) to Elucidate the Catalytic Mechanism of Fructofuranosidases. [PDF]

Foods
Chen GL, Chen J, Zhao LZ, Lin B, Zheng FJ, Verma KK, Yang LF.   +6 more
europepmc   +1 more source

Oral glucocorticoid dose patterns and organ damage in systemic lupus erythematosus – a nationwide cohort study

Arthritis &Rheumatology, Accepted Article.
Background Evaluating the relationship between glucocorticoid (GC) exposure and organ damage in systemic lupus erythematosus (SLE) is challenging since GC dose varies over time. It is unclear which exposure time window captures the full impact of GC usage.
Annica Dominicus, Álvaro Gomez, Ngoc V. Nguyen, Karin Blomkvist Sporre, Francesca Faustini, Elisabet Svenungsson, Elizabeth V. Arkema   +6 more
wiley   +1 more source

Characterization of resistance to last-line therapeutic molecules and genetic diversity of <i>Klebsiella</i> spp. strains involved in urinary tract infections in women: the case of Hôpital d'Instruction des Armées Omar Bongo Ondimba. [PDF]

J Med Microbiol
Mayombo Ngoussou E, Dikoumba AC, Mambu M, Mabika Mabika R, Zong Minko O, Mounioko F, Ondjiangui LF, Moyen R, Yala JF.   +8 more
europepmc   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Automated real-time feeding control for microbial electrolysis cell-anaerobic digestion systems using finite state machine. [PDF]

Sci Rep
Rutland H, Bowman K, Fudge T, Crossley E, Kyazze G, Liu H, You J.   +6 more
europepmc   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Aversive 22-kHz ultrasonic vocalization playback reveals differences in affective (dys)function following early life adversity in male and female juvenile rats. [PDF]

Behav Brain Res
Bonauto SM, Wilson PL, Honeycutt JA.
europepmc   +1 more source

Caveolin‐1 enriched apoptotic bodies derived from oral hard palate orchestrate bone remodeling to treat heterotopic ossification

BMEMat, EarlyView.
Downregulated CAV1 in HO is restored via apoptotic bodies from PMSCs, which reprogram bone remodeling by delivering CAV1 to target cells, highlighting the therapeutic role of EV subtypes in heterotopic ossification. Abstract Heterotopic ossification (HO) is a pathological process characterized by ectopic bone formation in non‐osseous tissues, with an ...
Yuchen Wang, Like Tang, Zhou Yu, Wenjin Cai, Qifeng Jiang, Zhikang Wang, Yitong Chen, Kaichen Lai, Ying Wang, Tim Forouzanfar, Chiyuan Ma, Gang Wu, Tingben Huang, Guoli Yang   +13 more
wiley   +1 more source