Results 91 to 100 of about 4,760 (166)

Repeated Treadmill Run Preconditioning Induces Prolonged Attenuation of Craniofacial Pain-like Behaviors and Changes in Brain Responses Associated with Persistent Craniofacial Inflammation in Male Mice. [PDF]

Biomedicines
Yusuf ASH, Hasegawa M, Iwamoto Y, Kato T, Anugrah A, Kakihara Y, Yamamura K, Okamoto K.   +7 more
europepmc   +1 more source

A Stable Isopterin Mimic of a Potent Bacterial Stimulant of T Cells

Chemistry – A European Journal, EarlyView.
A microbial metabolite covalently binds immunological protein MR1 to potently activate specific lymphocytes called MAIT cells, but it is too unstable for biological applications. Here, using synthesis, assays, protein crystallography, and computer modelling, we report a water‐stable analogue that activates reporter cells expressing the MAIT T cell ...
Jeffrey Y. W. Mak, Huy N. Hoang, Wael Awad, Xin Yi Lim, Damica D. Laurie, Ryan J. D. Rivero, James McCluskey, Alexandra J. Corbett, Jamie Rossjohn, David P. Fairlie   +9 more
wiley   +1 more source

Development of an automated REM sleep deprivation device for mice in neuroscience research. [PDF]

HardwareX
Yang R, Morse WD, Zhong P.
europepmc   +1 more source

Tailoring Liquid Crystalline Self‐Assembly and Photophysical Properties of Unsymmetrical Fluorenones via Polar Terminal Groups

Chemistry – A European Journal, EarlyView.
Novel liquid crystalline fluorenones bearing various head groups were synthesized and characterized. By alteration of the head group, N, SmC, or SmA phases were obtained, and emission properties could be tuned depending on solvent or temperature. ABSTRACT In this work, a series of novel unsymmetrical fluorenone derivatives bearing various head groups ...
Falk Feucht, Franziska Müller, Johanna Osterbrink, Anna Zens, Yann Molard, Sabine Laschat   +5 more
wiley   +1 more source

MitoTex (Mitochondria Texture Analysis User Interface): Open-Source Framework for Textural Characterization and Classification of Mitochondrial Structures. [PDF]

Int J Mol Sci
Kaianathbhatta A, Al Daraawi M, Kunchur NN, Mejlaoui R, Versey Z, Cassol E, Mostaço-Guidolin LB.   +6 more
europepmc   +1 more source

Designing Threefold π‐Surfaces Through Peripheral Halogenation to Shape Multidirectional Molecular Packing

Chemistry – A European Journal, EarlyView.
The complete series of hexahalogenated triptycene‐tribenzoquinones, comprising newly synthesized fluoro‐, bromo‐, and iodo‐substituted derivatives together with the previously reported chloro analogue, enables systematic comparison of their molecular properties and intermolecular interactions in relation to their crystal packing modes.
Shuta Tsuruga, Kenzo Suzuki, Hiromichi Yokoyama, Yoshiaki Shoji, Takanori Fukushima   +4 more
wiley   +1 more source

Spinal glycine receptor alpha 1 coordinates startle behavior through a cell-type specific mechanism. [PDF]

Int J Biol Sci
Wei S, Xu J, Chen SR, Huang Y, Jarrett Z, Godlewski G, Paloczi J, Pacher P, Pan HL, Xu Y, Lovinger DM, Zhang L.   +11 more
europepmc   +1 more source

Chemical engineering as an essential element of industrial biotechnology in Mexico: New aims in research and university education

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract On the centennial of higher education in Chemical Engineering in Mexico, it is pertinent to revisit the key stages that have contributed to its consolidation as a vital discipline for the nation's scientific and technological advancement. Although the initial mission of chemical engineering education was primarily oriented toward the training ...
Agustín López Munguía, Octavio T. Ramírez, Rafael Vazquez‐Duhalt, Eduardo Bárzana   +3 more
wiley   +1 more source

Dexmedetomidine Rapidly Relieves Stress-Induced Hyperalgesia via Presynaptic <i>α</i>2-Adrenergic Inhibition at Orbitofrontal-Insular Glutamatergic Synapses. [PDF]

MedComm (2020)
Rong H, Zhang YX, Zhu H, Li Y, Hou Y, Xie YY, Li LY, Zhang BB, Xie ST, Zhang W, Zhang QP, Zhang XY, Zhu JN, Gu X, Ma Z.   +14 more
europepmc   +1 more source

GRIA2 Variant Associated With Paradoxical Response to Perampanel Expanding the Spectrum of GRIA2‐Related Epileptic Encephalopathy: Case Report and Literature Review

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction GRIA2 encodes the GluA2 ionotropic α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid (AMPA) receptor subunit. Pathogenic GRIA2 variants cause epilepsy, developmental delay, and neurobehavioral disorders. Characterizations of clinical features, including seizure types and their treatments, in patients with GRIA2‐related ...
Sai Srihitha Dommata, Chhitij Tiwari, Zheng Fan, Muge Gucsavas‐Calikoglu, Yael Shiloh‐Malawsky, Kimberly S. Foss, Stephanie N. Peck, Erin L. Heinzen, Chon Lee, Senyene E. Hunter   +9 more
wiley   +1 more source