Results 111 to 120 of about 4,273 (169)

Assessing the validity of leucine zipper constructs predicted by AlphaFold. [PDF]

Protein Sci
Mitic I, Rowell K, Litfin T, Michie KA, Jacques DA.   +4 more
europepmc   +1 more source

Proteomic Profiling of Primary Hippocampal Neurons Reveals Noncanonical GFAP Expression and Metabolic Adaptations in Glia‐Free Culture

PROTEOMICS, EarlyView.
ABSTRACT Despite their widespread use as a research model, a comprehensive, quantitative proteomic profile of the cultured hippocampal neurons has remained unexplored. Here, we provide the first global proteomic characterization of primary murine hippocampal neurons cultured for 14 days under near‐physiological glucose conditions (2.5 mM).
Dominika Drulis‐Fajdasz, Kinga Gostomska‐Pampuch, Natalia Pudełko‐Malik, Mariusz Fleszar, Agnieszka Gizak, Jacek R. Wiśniewski, Dariusz Rakus   +6 more
wiley   +1 more source

Ischemic Stroke Incidence and Severity and Poststroke Cognitive Decline and Incident Dementia.

JAMA Netw Open
Koton S, Gross AL, Aparicio HJ, Beiser AS, Briceño EM, Coresh J, Elkind MSV, Giordani BJ, Gottesman RF, Hayward RA, Howard VJ, Johansen MC, Lazar RM, Springer MV, Stanton RJ, Sussman J, Wang H, Whitney RT, Ye W, Levine DA.   +19 more
europepmc   +1 more source

Engaging Gut-to-Brain Signalling to Treat Alcohol Use Disorder. [PDF]

Addict Biol
Hoffman PL, de Guglielmo G, Vengeliene V, Kunze W, Lebonville CL, Swinny JD, Roberts AJ, George O, Neufeld KM, Dunbar A, Saba LM, Ma R, Vendruscolo LF, Becker HC, Spanagel R, Tabakoff B.   +15 more
europepmc   +1 more source

Made in the shade: Leaf responses of native wildflowers to single‐axis photovoltaic solar energy

PLANTS, PEOPLE, PLANET, EarlyView.
As solar energy expands globally, balancing renewable power generation with biodiversity and ecosystem health has become an urgent challenge. This study investigated how native wildflowers respond at leaf level to the unique microclimates created by rotating solar panels in California's Central Valley.
Yudi Li, Troy Magney, Alona Armstrong, Rebecca R. Hernandez   +3 more
wiley   +1 more source

Control of feeding behavior by modified retrograde AAV to the gastrointestinal tract nerve afferents. [PDF]

Sci Rep
Marongiu R, Wang J, Unda SR, Barbera J, Velazquez L, Li R, Jimenez-Gonzalez M, Tower W, de Silva N, Retik R, Stanley SA, Kaplitt MG.   +11 more
europepmc   +1 more source

A Gene Expression Tumor Signature Optimizing Partial Area‐Under‐the‐Curve (pAUC) to Improve Specificity for Indolent Prostate Cancer

The Prostate, EarlyView.
ABSTRACT Purpose A key clinical challenge in prostate cancer is the identification and validation of biomarkers with high specificity for indolent long‐term outcomes. We applied a novel statistical method to identify tumor transcriptomic biomarkers that optimally predicted patients with low metastatic potential.
Travis A. Gerke, Svitlana Tyekucheva, Konrad H. Stopsack, Christopher J. Sweeney, Rosina T. Lis, Elizabeth N. Westling, Massimo Loda, Meir J. Stampfer, Kathryn L. Penney, Giovanni Parmigiani, Lorelei A. Mucci   +10 more
wiley   +1 more source

Assessment of dispersion metrics for estimating single-cell transcriptional variability. [PDF]

PLoS Comput Biol
Chen T, Boyer LA, Agarwal D.
europepmc   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source