Housing environment bilaterally alters transcriptomic profile in the rat hippocampal CA1 region. [PDF]
Kubota A +7 more
europepmc +1 more source
Multi‐level fatigue reliability assessment of reinforced concrete railway bridges
Abstract This paper presents a multi‐level reliability framework for assessing the fatigue life of reinforced concrete (RC) railway trough bridges subjected to cyclic loading. The framework incorporates increasing levels of analytical complexity and real‐world data in four steps. First, an analytical model applies S–N curves and the Palmgren–Miner rule
Silvia Sarmiento +7 more
wiley +1 more source
The experiences of podiatrists prescribing custom foot orthoses and patients using custom foot orthoses for foot pain management in the United Kingdom: A focus group study. [PDF]
Leach E, Cowley E, Bowen C.
europepmc +1 more source
ABSTRACT The current study aimed to quantify the antimicrobials amoxicillin (AMX), cefazolin (CFZ), chloramphenicol (CHL), metronidazole (MTZ), and sulfamethoxazole (SX) in effluents and surface water of an important Cerrado river, calculate their half‐lives, and analyze their ecotoxicity following single and combined exposures.
Náthala Maria Simão +12 more
wiley +1 more source
Effects of methotrexate on Wnt/β-catenin signaling and glial activation in temporomandibular joint arthritis in rats. [PDF]
de Figueiredo Costa AC +6 more
europepmc +1 more source
Understanding how prey species tradeoff predation risk and resource acquisition is particularly important for advancing our knowledge of predator–prey relationships. We investigated this by studying the use of concentrated anthropogenic resources, namely supplementary feeding sites, by roe deer Capreolus capreolus before and after grey wolf Canis lupus
Federico Ossi +7 more
wiley +1 more source
Inference of Genetic Networks from Pseudo Time Series of Single-cell Gene Expression Data using Modified Random Forests. [PDF]
Kimura S +4 more
europepmc +1 more source
Structural insights into the binding mode of the hypnotic drug vornorexant to orexin receptors
The crystal structure of the human orexin type 2 receptor–vornorexant complex (3.29 Å resolution) and orexin type 1 receptor docking revealed a conserved U‐shaped binding conformation, explaining the high affinity and balanced dual antagonism of this dual orexin receptor antagonist. The structural data validate the rational design that incorporated a 1,
Masashi Mima +4 more
wiley +1 more source
Medial preoptic CCKAR mediates anxiety and aggression induced by chronic emotional stress in male mice. [PDF]
Tang MY +13 more
europepmc +1 more source
This article contributes to rethinking the dichotomy between informal sociality and ritual formality by examining the occasional ritual encounters surrounding spirit‐tablet inscription in Chinese Buddhist temples. Rather than viewing rituals as enactments of established orders, it presents ritual engagement as a contingent process of relational ...
Yang Shen
wiley +1 more source

