Results 81 to 90 of about 4,190 (169)

Spinal Dorsal Horn Neurons Receiving Descending Input from the Primary Somatosensory Cortex Contribute to Aβ Fiber-Induced Neuropathic Allodynia in Male Rats. [PDF]

Cells
Shinotsuka S, I E, Sueto D, Fujimori K, Yamaura K, Tsuda M.   +5 more
europepmc   +1 more source

Assessing the validity of leucine zipper constructs predicted by AlphaFold. [PDF]

Protein Sci
Mitic I, Rowell K, Litfin T, Michie KA, Jacques DA.   +4 more
europepmc   +1 more source

Control of feeding behavior by modified retrograde AAV to the gastrointestinal tract nerve afferents. [PDF]

Sci Rep
Marongiu R, Wang J, Unda SR, Barbera J, Velazquez L, Li R, Jimenez-Gonzalez M, Tower W, de Silva N, Retik R, Stanley SA, Kaplitt MG.   +11 more
europepmc   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Machine learning-enhanced discovery of a basement membrane-related gene signature in glioblastoma via single-cell and Spatial transcriptomics. [PDF]

J Transl Med
Liu Z, Yang Y, Fang H, Han M, Qi P, Fan Y, Li J, He S, Wang L.   +8 more
europepmc   +1 more source

Tumor‐Intrinsic Forkhead Box A2 Regulates the Lymph Node Metastasis of Papillary Thyroid Carcinoma by Regulating T‐Cell Apoptosis

iLABMED, EarlyView.
We identified FOXA2 as a key regulator of lymph node metastasis in thyroid cancer, which controls cancer cell aggressiveness. FOXA2 knockdown promotes metastasis by enhancing tumor cell migration and, importantly, by inducing T‐cell apoptosis through a CCL2/LCN2‐mediated pathway. Created with BioGDP.com.
Ping Yang, Xueying Zhang, Wen Deng, Fangning Gao, Shujia Peng, Guoqiang Bao, Lijuan Yuan   +6 more
wiley   +1 more source

Descending projections from the insular cortex to the lateral parabrachial nucleus facilitate nocifensive behaviors in rats. [PDF]

Pain
Nakaya Y, Hirose K, Kitano K, Zhao G, Kobayashi A, Osaki H, Kobayashi M.   +6 more
europepmc   +1 more source

Napabucasin transforms liver microenvironment and boosts immunotherapy efficacy by converting potential metastases into “hot” tumors

Interdisciplinary Medicine, EarlyView.
Napabucasin reduces liver metastases by reprogramming the hepatic microenvironment. It induces hepatocyte secretion of CCL21 via c‐Fos activation, recruiting lymphocytes and converting “cold” metastases into immunologically “hot” tumors. This effect is liver‐specific and independent of cancer cells.
Qiongqiong Wang, Jiaqi Zhou, Hang Qiao, Yifan Jia, Ling Ye, Zeli Li, Jiahe Ouyang, Haoxian Zhou, Kangxin Zeng, Xuemeng Wang, Yixian Wang, Yang Zhang, Yupeng Zhang, Yizhou Cai, Yutao Hu, Minzhe Zhang, Wenwei Xu, Zhenzhen Wu, Xiaofang Qiu, Li Lin   +19 more
wiley   +1 more source

DD-CC-II: Data Driven Cell-Cell Interaction Inference and Its Application to COVID-19. [PDF]

Int J Mol Sci
Park H, Miyano S.
europepmc   +1 more source

Automated Creak Identifies Laryngeal Dystonia During Conversational Speech

The Laryngoscope, EarlyView.
This study evaluated whether automated creak distinguished speakers with adductor laryngeal dystonia (AdLD), muscle tension dysphonia (MTD), and those without voice disorders during conversational speech. Automated creak estimates were able to differentiate speakers with AdLD from MTD and controls with similar performance across different types of ...
Daria A. Dragicevic, Cara E. Sauder, Daniel P. Buckley, Laura E. Toles, Lauren F. Tracy, J. Pieter Noordzij, Gregory A. Grillone, Ted Mau, John Paul Giliberto, Tanya K. Meyer, Albert L. Merati, Tanya L. Eadie, Cara E. Stepp, Katherine L. Marks   +13 more
wiley   +1 more source