Results 51 to 60 of about 1,422 (172)

Antioxidant Activity, Carbohydrate‐Hydrolysing Enzyme Inhibition, Antihyperglycaemic Effect and Associated Expression Changes of Bryophyllum pinnatum‐Fortified Wheat‐Plantain Snack in Streptozotocin‐Induced Diabetic Rats

open access: yesFood Chemistry International, EarlyView.
The developed wheat‐plantain‐based snack with Bryophyllum pinnatum had enhanced antioxidant properties, with high α‐amylase and α‐glucosidase enzyme inhibitory activities. When fed to STZ‐induced diabetic rats, it showed antidiabetic, hypo‐lipidaemic and anti‐inflammatory potentials, thus making it a fresh opportunity for the snacking community who are
G. M. Ogungbenro   +6 more
wiley   +1 more source

Gut Enterococcus faecium derived leucic acid mediates the antiobesity effect of dietary fiber

open access: yesiMeta, EarlyView.
This study identified Enterococcus faecium as a gut bacterium with anti‐obesity activity, which alleviated adipocyte hypertrophy, dyslipidemia, and hepatic steatosis by converting leucine into leucic acid (LEA) to regulate mitochondrial oxidative phosphorylation.
Baifei Hu   +9 more
wiley   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

open access: yesiNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong   +5 more
wiley   +1 more source

Stripping‐based approach for the recovery of volatile fatty acids from anaerobic digestion digestate: preliminary experimental investigations and modelling

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Volatile fatty acids (VFAs) are widely used across industries: as intermediates in chemical production (e.g., solvents and polymers), in pharmaceuticals and cosmetics, and as preservatives and health‐promoting additives in food and animal feed. Emerging applications also include bioplastics, bioenergy, and biotechnology.
Simeone Chianese   +6 more
wiley   +1 more source

Spatio‐Temporal Analysis of Human Thermal Comfort and Relationships With Large‐Scale Climate Indices Along Ghana's Coastal‐Urban Corridor From 1980 to 2020

open access: yesInternational Journal of Climatology, EarlyView.
Four decades of UTCI data show increasing thermal stress along Ghana's coastal‐urban corridor, with very strong heat‐stress days rising by about 1.4 days/year. Random Forest–SHAP analysis with temporal validation identified AOD as the strongest model‐based predictor of monthly UTCI variability, followed by TSA, WHWP, and AMO.
Kwadwo Frimpong   +3 more
wiley   +1 more source

Early Growth Response 1‐Associated Epithelial Autophagy‐Related Changes in Allergic Airway Inflammation

open access: yesPediatric Discovery, EarlyView.
House dust mite (HDM) exposure induces early growth response 1 (EGR1) expression in airway epithelial cells and is accompanied by autophagy‐associated alterations, including increased LC3B‐II and Vps34 levels and decreased p62 abundance. Manipulation of EGR1 expression modulates these autophagy‐related changes, whereas pharmacological inhibition of ...
Xinyang Wang   +3 more
wiley   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

open access: yesPhytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li   +14 more
wiley   +1 more source

Closed‐form solutions for dynamic punching shear assessment in flat slabs subjected to sudden column removal

open access: yesStructural Concrete, EarlyView.
Abstract Simplified closed‐form equations are commonly used in structural design to prevent punching shear failures of concrete flat slabs supported on columns in permanent and transient situations, whereas more advanced methods are generally used in verifications at accidental design situations due to the lack of suitable equivalent approaches ...
Maria Liapopoulou   +3 more
wiley   +1 more source

Antimicrobial Residues in a Key Cerrado River: Distribution, Persistence, and Effects on Zebrafish Embryo‐Larval Development

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT The current study aimed to quantify the antimicrobials amoxicillin (AMX), cefazolin (CFZ), chloramphenicol (CHL), metronidazole (MTZ), and sulfamethoxazole (SX) in effluents and surface water of an important Cerrado river, calculate their half‐lives, and analyze their ecotoxicity following single and combined exposures.
Náthala Maria Simão   +12 more
wiley   +1 more source

Intellectual Property Restitution

open access: yesThe Modern Law Review, EarlyView.
In Europe, open GLAM movements and cultural restitution reforms are overlooking a crucial aspect that should not be underestimated: what should happen to the archival materials, digital collections and intellectual property that are indelibly linked to cultural property.
Andrea Wallace, Mathilde Pavis
wiley   +1 more source

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