Binuclear Copper‐Dependent Oxidative Enzymes Involved in Fungal Natural Product Modifications
This article summarizes recent biochemical characterizations of a new enzyme family named by the authors as binuclear copper‐dependent oxidative enzymes (BiNCOs). Found in fungal natural product biosynthesis, BiNCOs catalyze diverse CH functionalization reactions, including C(sp3)H halogenation, C(sp3)H hydroxylation, C(sp3)O macrocyclization, and ...
Chen‐Yu Chiang, Masao Ohashi, Yi Tang
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Neuromodulatory Effects of Substantia Nigra Pars Reticulata Deep Brain Stimulation (SNr-DBS) in the 6-Hydroxydopamine Rat Model of Parkinson's Disease. [PDF]
Turgut E +9 more
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Single‐cell RNA‐seq of normal and endometritis endometrium shows reduced epithelial cells and fate divergence toward ferroptosis or ribosome/antigen‐presentation programs. COL1A1+ epithelial cells act as an AP‐1–driven hub that enhances VEGFA–VEGFR signaling and remodels the vascular microenvironment.
Chengzi Tian, Zaiyi Li
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Exercise type-brain region interactions determine the effects of exercise on the hippocampus. [PDF]
Tsuchida R +4 more
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A 79‐year‐old man presented with massive pleural effusion in which cytological examination revealed lymphoma cells without evidence of a solid tumor mass. Negative EBV in situ hybridization and negative HHV8 and HIV testing, combined with flow cytometric immunophenotyping and molecular findings, supported a diagnosis of fluid overload–associated large ...
Van Vlierberghe Magalie +5 more
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Innovative Immobilization of <i>Aspergillus aculeatus</i> OI4C2 Fructosyltransferase on MANAE-Agarose Cross-Linked with Genipin for Enhanced Production of Fructooligosaccharides. [PDF]
Inagaki TS +10 more
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Integrated macroscopic, histological, and ultrastructural analyses revealed five distinct lingual papillae types (filiform, fungiform, conical, foliate, and vallate) in the Anatolian wild boar (Sus scrofa libycus). Mechanical papillae showed marked structural specialization, while gustatory papillae exhibited region‐specific distribution of taste buds.
Fatma Işbilir +4 more
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Miniaturized optically generated Bessel beam ultrasound for volumetric transcranial brain stimulation. [PDF]
Li Y +10 more
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Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
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The promising regenerative potential of pulsed electromagnetic fields toward tendon differentiation : a hamstring tendon explant culture study. [PDF]
Marmotti A +10 more
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