Results 121 to 130 of about 36,074 (165)

Targeting KPC-Producing <i>Klebsiella pneumoniae</i> Biofilms: Genomic Profiles, Clinical Outcomes and Novel Combinations. [PDF]

Microorganisms
Papalini C, Bicchieraro G, Tordelli Ruda L, Wong AYW, Battistelli C, Genga G, Tommasi A, Gidari A, Francisci D, Socio GV, Spaccapelo R, Pietrella D, Mencacci A, Monari C, Sabbatini S.   +14 more
europepmc   +1 more source

Anterior cingulate cortex neuron subtypes differentially regulate seizures

Epilepsia, EarlyView.
Abstract Objective This study aimed to investigate the regulatory roles of distinct neuronal subtypes within the anterior cingulate cortex (ACC) in acute seizures and to identify cell type‐specific mechanisms underlying seizure modulation in this region. Methods Acute seizure models were established in mice via pentylenetetrazol injection.
Ziqian Yan, Ting Tang, Kaishan Wang, Bin Fu, Zesheng Li, Mingshan Liu, Hongyi Huang, Yanfeng Yang, Qiang Zheng, Yangmin Zheng, Yongzhi Shan, Yumin Luo, Guoguang Zhao   +12 more
wiley   +1 more source

Kappa opioids suppress histaminergic itch by inhibiting mediodorsal thalamus-projecting claustrum glutamatergic neurons. [PDF]

Sci Adv
Liu Z, Shu X, Wang Z, Yao S, Hu C, Wang B, Liu P, Feng L, Shen Y, Xiao H, Liu JG, Wang YJ.   +11 more
europepmc   +1 more source

Transcranial Direct Current Stimulation Targeting the Primary Motor Cortex Suppresses Activity in the Ventrolateral Periaqueductal Gray and Alleviates Chronic Pain in a Rat Model of Knee Osteoarthritis. [PDF]

J Pain Res
Xu Y, Fan C, Xue J, Gao C, Zhou Y, Li T.
europepmc   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Characterization of resistance to last-line therapeutic molecules and genetic diversity of <i>Klebsiella</i> spp. strains involved in urinary tract infections in women: the case of Hôpital d'Instruction des Armées Omar Bongo Ondimba. [PDF]

J Med Microbiol
Mayombo Ngoussou E, Dikoumba AC, Mambu M, Mabika Mabika R, Zong Minko O, Mounioko F, Ondjiangui LF, Moyen R, Yala JF.   +8 more
europepmc   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Core transcriptional regulatory circuitry identified from patient-derived tumor cells provides a specific vulnerability for rhabdomyosarcoma. [PDF]

Cell Death Dis
Liu S, He Z, Chen X, Tang Y, He M, Zhang L, Xu W, Wang J, Tao T.   +8 more
europepmc   +1 more source

Application of Enzyme Engineering and Synthetic Biology for Modulated Transformation of Fructooligosaccharides (FOSs) to Elucidate the Catalytic Mechanism of Fructofuranosidases. [PDF]

Foods
Chen GL, Chen J, Zhao LZ, Lin B, Zheng FJ, Verma KK, Yang LF.   +6 more
europepmc   +1 more source

Novel Long-Acting Ghrelin Analogue PEP-064 Restores Energy Balance in C26 and Lewis Lung Carcinoma-Induced cachexia in Mice. [PDF]

J Cachexia Sarcopenia Muscle
Hunt JE, Lund C, Chen B, Diaz AR, Dmytriyeva O, Marcotorchino J, Löbner K, Mörl K, Andersen NR, Ogueboule ZKJ, Frank E, Stöhr J, Meseguer D, Panajotova V, Roux J, Clemmensen C, Sylow L, Schneeberger M, Beck-Sickinger AG, Pedersen SL, Fosgerau K.   +20 more
europepmc   +1 more source