Results 61 to 70 of about 653 (160)

Molecular Basis and Clinical Spectrum of WNT10A‐Related Oligodontia

open access: yesClinical Genetics, Volume 110, Issue 1, Page 3-14, July 2026.
Cellular Mechanism behind WNT10A phenotypes. ABSTRACT WNT10A mutations, a major genetic determinant of dental agenesis and ectodermal dysplasia, exert profound effects on craniofacial development. Although classified as rare disorders, these mutations account for more than half of oligodontia cases, reflecting their critical role.
Perennes Elise   +5 more
wiley   +1 more source

Theorizing Patriarchy Against a Backdrop of Workplace Sexism and Stress in UK Academia

open access: yesGender, Work &Organization, Volume 33, Issue 4, Page 1480-1492, July 2026.
ABSTRACT Our analysis investigates the distinct relationship between sexism and workplace stress as experienced by women academics in the UK higher education system. We argue that due to the insufficient literature on this issue there is a limited knowledge base of the harmful psychological effects of stress in the workplace upon women academics in the
Andrew Baron, Charlotte Barrow
wiley   +1 more source

Reframing Wnt/β‐Catenin Signalling in Liver Fibrosis: Transcriptional State Regulation by CBP and p300

open access: yesLiver International, Volume 46, Issue 7, July 2026.
ABSTRACT Liver fibrosis is a shared pathological phenotype of chronic liver diseases of diverse etiologies, including viral hepatitis, alcohol‐associated liver disease and metabolic dysfunction–associated steatohepatitis (MASH), as well as cholestatic liver diseases such as primary biliary cholangitis and primary sclerosing cholangitis, and may ...
Kiminori Kimura, Michinori Kohara
wiley   +1 more source

Epigenetically driven impairment of BDNF–ARC signaling contributes to circadian and cognitive disarray in a mouse model of postoperative delirium

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Postoperative delirium (POD) is common in older surgical patients and is clinically associated with an increased risk of long‐term cognitive decline and dementia; disrupted BDNF signaling and circadian dysregulation are implicated, but their coordinated mechanisms remain unclear.
Hari Prasad Osuru   +7 more
wiley   +1 more source

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

open access: yesFood Biomacromolecules, Volume 3, Issue 2, Page 237-251, June 2026.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

The Role of Neutrophils and NETosis in Diseases: The Implications for Therapy

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Neutrophils secrete cytokines, express specific surface proteins, increase or decrease in cell count, and their ratio to lymphocyte count can be used as biomarkers to characterize collective status and disease progression. Neutrophils can monitor and track the body's health status, “Wei Bing” status, disease status, and different times of disease ...
Zhen Ma   +6 more
wiley   +1 more source

The Protein Phosphatase Inhibitor LB100 Targets the Mesenchymal Lineage of Pancreatic Ductal Adenocarcinoma

open access: yesMedComm, Volume 7, Issue 6, June 2026.
To define the mechanisms of sensitivity to PP2A inhibitors (PP2Ai), we combined molecular profiling of PP2Ai responses with genome‐wide genetic screens. PP2Ai preferentially target mesenchymal pancreatic ductal adenocarcinoma (PDAC) cells and engage pathways linked to transcriptional elongation, splicing, metabolism, and ER stress response factors ...
Janine Murr   +37 more
wiley   +1 more source

Direct Evidence for a Carbon–Carbon One‐Electron σ‐Bond, or a Weak Carbon–Carbon Interaction?

open access: yesChemistryOpen, Volume 15, Issue 6, June 2026.
Experiments reporting the existence of a single‐electron C─C σ bond in a synthesized stable radical cation open up new perspectives in the study of the existence of chemical bonds. However, the supporting theoretical results at density functional theory cost do not seem to fully support this evidence.
Costantino Zazza   +4 more
wiley   +1 more source

When invasions go unnoticed: Public perception of the freshwater jellyfish Craspedacusta sowerbii in Europe

open access: yesPeople and Nature, Volume 8, Issue 6, Page 1957-1973, June 2026.
Abstract Biological invasions are a major driver of biodiversity loss, yet inconspicuous or “cryptic” species often escape detection and public awareness, limiting management responses. We investigated the freshwater jellyfish Craspedacusta sowerbii, likely native to China and now present on six continents, through a 22‐month multilingual online survey
Guillaume Marchessaux   +17 more
wiley   +1 more source

A Combined Colon Organoid‐Sensory Neuron Model Reveals Epithelial Contribution to Moringin Efficacy Against Painful Inflammatory Bowel Disease

open access: yesPhytotherapy Research, Volume 40, Issue 6, Page 3250-3266, June 2026.
Experimental workflow and main findings of the study. ABSTRACT Visceral pain is a major symptom of inflammatory bowel diseases (IBDs), requiring effective treatment strategies. Gut epithelium, beyond maintaining barrier integrity and microbiota homeostasis, modulates neurosensorial circuitries, influencing visceral sensitivity.
Francesco Margiotta   +7 more
wiley   +1 more source

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