Results 11 to 20 of about 1,245 (98)

Multi‐level fatigue reliability assessment of reinforced concrete railway bridges

Structural Concrete, EarlyView.
Abstract This paper presents a multi‐level reliability framework for assessing the fatigue life of reinforced concrete (RC) railway trough bridges subjected to cyclic loading. The framework incorporates increasing levels of analytical complexity and real‐world data in four steps. First, an analytical model applies S–N curves and the Palmgren–Miner rule
Silvia Sarmiento, Jaime Gonzalez‐Libreros, Chao Wang, Lennart Elfgren, Ola Enoksson, Tommy Höjsten, Lars‐Olof Andersson, Gabriel Sas   +7 more
wiley   +1 more source

Cannabidiol and cannabigerol ameliorate steatotic liver disease via phosphocreatine buffering and lysosomal restoration

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) and cannabigerol (CBG) alleviate hepatic steatosis in obese mice by shifting energy buffering towards phosphocreatine and enhancing lysosomal lipid degradation and trafficking. These effects are associated with increased creatine kinase activity and lysobisphosphatidic acid (LBPA) levels, highlighting a previously unrecognised ...
Radka Kočvarová, Shahar Azar, Bella Agranovich, Ifat Abramovich, Saveliy Kirillov, Alina Nemirovski, Saja Baraghithy, Inbar Plaschkes, Emmanuelle Merquiol, Alexander Rouvinski, Galia Blum, Liad Hinden, Joseph Tam   +12 more
wiley   +1 more source

Angiotensin Receptor Blockers Versus Calcium Channel Blockers for First‐Line Antihypertensive Therapy and Survival in Adults Aged 75 Years or Older

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Evidence guiding first‐line antihypertensive drug choice in adults aged 75 years or older is limited, despite widespread use of angiotensin receptor blockers (ARBs) and calcium channel blockers (CCBs) in late older age. Methods We conducted a target trial emulation using a new‐user design in a nationwide linked healthcare claims ...
Hisashi Noma, Hiroshi Sunada, Taiki Sugimoto, Ken‐Ei Sada, Futoshi Oda, Megumi Maeda, Haruhisa Fukuda   +6 more
wiley   +1 more source

Sorption Isotherm Curves in Dry Extruded Pet Foods: Evaluation and Comparison With the Drying Curve

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Sorption isotherms evaluate water exchange between food and environments with different water activities (aw), providing valuable information on physical changes and susceptibility of deterioration due to lipid oxidation and microbial growth.
Mayara Uana da Silva, Anne Caroline Rocha Bernardino, Lucas Ben Fiuza Henríquez, Vanderly Janeiro, Ricardo Souza Vasconcellos   +4 more
wiley   +1 more source

Reading Dürer in Late Sixteenth‐Century Padua: Matteo Macigni (ca. 1510–1582), His Library and the Annotated Institutionum geometricarum (Paris, 1535)

Renaissance Studies, EarlyView.
ABSTRACT This article contributes to the history of material culture and intellectual biography by definitively identifying the Paduan scholar Matteo Macigni (ca. 1510–1582) as the author of the annotations found in a 1535 copy of Albrecht Dürer’s Institutionum geometricarum currently preserved in Vicenza.
Laura Moretti
wiley   +1 more source

Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition

The Journal of Physiology, EarlyView.
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin, Andrea Carrer, Federica Boscolo Nata, Elena Frigo, Federico Fogolari, Giovanna Lippe, Michela Carraro, Paolo Bernardi   +7 more
wiley   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

A Probabilistic Greedy Attempt to Be Fair in Neural Team Recommendation

Computational Intelligence, Volume 42, Issue 3, June 2026.
ABSTRACT Neural team recommendation has brought state‐of‐the‐art efficacy while enhancing efficiency at forming teams of experts whose success in completing complex tasks is almost surely guaranteed. However, they overlook fairness, that is, predicted teams are heavily biased toward popular and male experts, falling short of recommending female or ...
Hamed Loghmani, Mahdis Saeedi, Gabriel Rueda, Edwin Paul, Hossein Fani   +4 more
wiley   +1 more source

Infinity‐operadic foundations for embedding calculus

Journal of Topology, Volume 19, Issue 2, June 2026.
Abstract Motivated by applications to spaces of embeddings and automorphisms of manifolds, we consider a tower of ∞$\infty$‐categories of truncated right modules over a unital ∞$\infty$‐operad O$\mathcal {O}$. We study monoidality and naturality properties of this tower, identify its layers, describe the difference between the towers as O$\mathcal {O}$
Manuel Krannich, Alexander Kupers
wiley   +1 more source

Chromatin unwinding state for in situ identification and lineage tracing of circulating tumor cells

iMeta, Volume 5, Issue 2, April 2026.
The detection of circulating tumor cells (CTCs) through liquid biopsy offers a non‐invasive approach for accurately monitoring cancer dissemination and evaluating therapeutic efficiency. However, their rarity and heterogeneity limit conventional tumor antigen labelling‐based methods in identifying and tracing CTCs.
Bin Ye, Zhen Wang, Yinqi Bai, Xu Zhang, Rui Zhang, Jingru Lian, Xuefei Liu, Yan Zhang, Zhiyuan Xu, Li Yang, Haiman Jin, Fang Chen, Zhihao Xie, Ping Zhou, Jun Tan, Shan Zeng, Changzheng Du, Yang Min, Xiaomin Ni, Jingxian Duan, Zhicheng Li, Hui Yang, Yunpeng Cai, Hongyan Wu, Catherine C. Liu, Jing Cai, Yi Lu, Jian Zhang, Hao Wu, Hairong Zheng, Longqi Liu, Xin Hong, Hao Yu   +32 more
wiley   +1 more source