Results 61 to 70 of about 4,078 (217)
Hepatology, EarlyView., 2022 Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong +9 more
wiley +1 more source
Development of fiber Bragg grating based inclinometer designs
, 2017 Following the massive and rapid infrastructures construction in Singapore’s dense urban plot, there is a rising demand for the monitoring of geographical condition around the construction site. As the on-going projects may have interference to the safety
Yao, Yuan
core
Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair
Advanced Science, EarlyView.Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li +9 more
wiley +1 more source
Effect of hysteresis on the stability of residual soil slope
, 2018 Soil-water characteristic curve (SWCC) plays an important role in the application of unsaturated soil mechanics. Matric suction in an unsaturated soil changes with varying climatic conditions associated with cyclic drying and wetting conditions ...
Kristo, Christofer
core
, 2016 Structural health monitoring (SHM) techniques using smart materials are on the rise to meet the ever ending demand due to increased construction and manufacturing activities worldwide.
Maheshwari, Muneesh
core +1 more source
Advanced Science, EarlyView.WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang +6 more
wiley +1 more source
Advanced Science, EarlyView.This study integrates two complementary traditional Chinese medicine components as precursors to synthesize bioactive AM‐AS@CDs. Compared with single‐component CDs, these dual‐component CDs exhibit enhanced antioxidant capacity and superior renoprotective effects.
Bixiao Liu +10 more
wiley +1 more source
Advanced Science, EarlyView.Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong +12 more
wiley +1 more source
Engineering neuromuscular tissues for bidirectional neuroprosthetic interfacing
, 2020 This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Thesis: Ph. D.
Srinivasan, Shriya, author.
core
, 2017 The stability of most earth embankments is strongly influenced by the water content of the soil. The water content directly influences the suction or pore pressure in the soil, as well as the mass of material, thereby affecting the stress state and ...
Vardon, P.J. (author) +7 more
core +1 more source