Results 51 to 60 of about 20,989 (216)

FilipeChagasDev/register-by-constant-qft-adder:

open access: yes, 2022
Introduction This is a quantum algorithm I created that can be considered a simplified version of Draper's adder. This algorithm is described as a unitary operator $U+(c)$ such that $U+(c)|a\rangle = | a + c \pmod{2^N}\rangle$, where $|a\rangle$ is the ...
Filipe Chagas
core   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

open access: yesAdvanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters   +12 more
wiley   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

open access: yesAdvanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi   +13 more
wiley   +1 more source

AN INVESTIGATION INTO THE MOLECULAR BASIS OF DENGUE VIRUS ATTENUATION IN ITS NATURAL HOSTS

open access: yes, 2021
Ph.DDOCTOR OF PHILOSOPHY ...
TANAMAS SIRIPHANITCHAKORN
core  

Musashi-2, a novel oncoprotein promoting cervical cancer cell growth and invasion, is negatively regulated by p53-induced miR-143 and miR-107 activation [PDF]

open access: yes, 2017
Background: Although previous studies have shown promise for targeting Musashi RNA-binding protein 2 (MSI-2) in diverse tumors, the role and mechanism of MSI-2 for cervical cancer (CC) progression and the regulation of MSI-2 expression remains unclear ...
Dong, Peixin   +9 more
core   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

open access: yesAdvanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu   +10 more
wiley   +1 more source

Implications of Copyright Evolution for the Future of Scholarly Communication and Grey Literature

open access: yes, 2006
Traditional practices regarding copyright are undergoing transformation. Although it is still common for scholars to give up their rights to their articles so that they will be published, this happens less frequently than it once did.

core  

Bahasa Indonesia

open access: yes, 2022
.  Fructooligosaccharides (FOS) are additives that are often used and utilized in the food, pharmaceutical, and chemical industries that have functional value for health. Lactobacillus plantarum B1765 has been known to have inulinase activity.
Natasya, Nur Wanda Aini   +3 more
core   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

open access: yesAdvanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang   +6 more
wiley   +1 more source

Impact on the growth parameters and microbial populations of probiotics and prebiotics on rabbits raised in the household system

open access: yes, 2021
The investigations and laboratory determinations were performed within the disciplines of Nutrition and Microbiology of the University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca.
Ștefănuț, Laura-Cristina   +7 more
core   +1 more source

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