Results 121 to 130 of about 486 (170)

Multi‐level fatigue reliability assessment of reinforced concrete railway bridges

Structural Concrete, EarlyView.
Abstract This paper presents a multi‐level reliability framework for assessing the fatigue life of reinforced concrete (RC) railway trough bridges subjected to cyclic loading. The framework incorporates increasing levels of analytical complexity and real‐world data in four steps. First, an analytical model applies S–N curves and the Palmgren–Miner rule
Silvia Sarmiento, Jaime Gonzalez‐Libreros, Chao Wang, Lennart Elfgren, Ola Enoksson, Tommy Höjsten, Lars‐Olof Andersson, Gabriel Sas   +7 more
wiley   +1 more source

Identification of a nuclear transcriptional module associated with ERα and E2F/FOXM1 signaling across PAM50 breast cancer subtypes. [PDF]

Front Oncol
Dozal-Luna AJ, Santuario-Facio SK, Cardona-Huerta S, Gómez-Macías GS, Rangel-Escareno C, Lira-Albarrán S, Gómez-Flores-Ramos L, Ortiz-López R.   +7 more
europepmc   +1 more source

A Model Based Systems Engineering Framework for Digital Twins in Medical Device Innovation

Systems Engineering, EarlyView.
ABSTRACT Medical device development remains constrained by development processes centered largely in the physical domain. These methods limited early understanding of system behavior and prolonged timelines relative to other innovation pathways. Such limitations increase prototype cycle duration and the number of iterations required to resolve design ...
Tanguy René Pinol, Leon Hugh Prentice, Kate Fox, Toh Yen Pang   +3 more
wiley   +1 more source

Targeting the gut microbiome for type 2 diabetes management: a scoping review of systematic reviews and meta-analyses. [PDF]

Front Endocrinol (Lausanne)
Jiang R, Zheng L, Fang J, Guan Q, Yuan H, Liang J, Zhang J, Han Q, Liu M.   +8 more
europepmc   +1 more source

Antimicrobial Residues in a Key Cerrado River: Distribution, Persistence, and Effects on Zebrafish Embryo‐Larval Development

Environmental Toxicology, EarlyView.
ABSTRACT The current study aimed to quantify the antimicrobials amoxicillin (AMX), cefazolin (CFZ), chloramphenicol (CHL), metronidazole (MTZ), and sulfamethoxazole (SX) in effluents and surface water of an important Cerrado river, calculate their half‐lives, and analyze their ecotoxicity following single and combined exposures.
Náthala Maria Simão, Igor Romeiro dos Santos, Jerônimo Raimundo de Oliveira Neto, Flávio Olimpio Sanches Neto, Felipe Cirqueira Dias, Jéssyca Moreira Morais, Lorranny Pereira de Assis Valadares, Naiara Raica Lopes de Oliveira, Mirelle Garcia Silva Bailão, Luiz Carlos da Cunha, Valter Henrique Carvalho‐Silva, Thiago Lopes Rocha, Elisa Flávia Luiz Cardoso Bailão   +12 more
wiley   +1 more source

Repeat-element RNAs integrate a neuronal growth circuit.

Cell
Zahavi EE, Koppel I, Kawaguchi R, Oses-Prieto JA, Briner A, Monavarfeshani A, Dalla Costa I, van Niekerk E, Lee J, Matoo S, Hegarty S, Donahue RJ, Sahoo PK, Ben-Dor S, Feldmesser E, Ryvkin J, Leshkowitz D, Perry RB, Cheng Y, Farber E, Abraham O, Samra N, Okladnikov N, Alber S, Albus CA, Rishal I, Ulitsky I, Tuszynski MH, Twiss JL, He Z, Burlingame AL, Fainzilber M.   +31 more
europepmc   +1 more source

Application of the miRNAs as biomarkers and therapeutic strategies in periodontal inflammation. [PDF]

Front Pharmacol
Saha S, Sachivkina N, Pilshchikova O, Muraev A, Ivanov S, Ivashkevich SG, Gurina R.   +6 more
europepmc   +1 more source

Research Progress on Upper Airway Cough Syndrome

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

A scheduling perspective on modular educational systems in Europe. [PDF]

Heliyon
Ruiz-Torrubiano R, Knopp S, Krystallidis A, Wolf LM.   +3 more
europepmc   +1 more source

Elements on the move: How ungulate migration expands Alpine biogeochemical footprints

Journal of Animal Ecology, EarlyView.
Using a spatially explicit model parameterized with GPS telemetry, we show that migratory and resident red deer play distinct roles in nitrogen redistribution across alpine landscapes. Migrants uniquely transport nitrogen upslope and up elevation, linking ecosystem element pools and revealing how the loss of migration alters large‐scale ecosystem ...
Kristy M. Ferraro, Andrea Corradini, Vivian Hawkinson, Olivier Chanel, Charles Figuières, Yann Bramoullé, Charlotte Vanderlocht, Federico Ossi, Davide Righetti, Oswald J. Schmitz, Francesca Cagnacci   +10 more
wiley   +1 more source