Results 101 to 110 of about 28,890 (169)

Hunting motivations, behaviour and forest access: Characterising wildlife hunting practices in a multi‐ethnic, forested landscape of Brunei Darussalam, Southeast Asia

People and Nature, EarlyView.
Abstract Unsustainable hunting practices can alter population dynamics, driving biodiversity declines, which leads to ‘empty forests’. Understanding hunting behaviour, including motivations for hunting and relationships with market drivers, and access to hunting grounds are important to develop affirmative policies to stem biodiversity loss.
Natasha L. M. Mannion, Rachel Gaulton, Maria Erica Jamil, Marion Pfeifer, Johan Willem Ferry Slik, Stephen G. Willis, F. Merlin Franco   +6 more
wiley   +1 more source

HEXIM1/P-TEFb complex controls RNA polymerase II pause release and immediate early gene induction following neuronal depolarization. [PDF]

J Biol Chem
Htet M, Estay-Olmos C, Hu L, Wu Y, Powers BE, Campbell CD, Rameshwar A, Ahmed MR, Hohman TJ, Wang Y, Schneider JA, Bennett DA, Menon V, De Jager PL, Kaas GA, Colbran RJ, Greer CB.   +16 more
europepmc   +1 more source

Engaging the public in plant science: Communication facilitators and barriers of scaling up a citizen science campaign

People and Nature, EarlyView.
Abstract Volunteers have been involved in nature observations for decades through citizen science initiatives, providing large data sets as well as problem identification that allow a more complete understanding of many natural phenomena. Although communication is a core component in citizen science, the key factors that determine its effectiveness in ...
Kristiina Gibson, Monika Suškevičs, Baiba Prūse, Marta Barberis, Sara A. O. Cousins, Živa Fišer, Margaux Julien, Marianne Kivastik, Marcin Klisz, Attila Lengyel, Zuzana Münzbergová, Radosław Puchałka, Iris Reinula, Froukje Rienks, Julie Koch Sheard, Viktor Siverin, Bojana Stojanova, Sabrina Träger, Tsipe Aavik   +18 more
wiley   +1 more source

Phenotypic and Molecular Analysis of Fosfomycin Resistance Among <i>P. aeruginosa</i> Isolates from Cystic Fibrosis Patients. [PDF]

Infect Drug Resist
Poormehr P, Behzadi A, Talebi Ahoi M, Khanbabaee G, Hakemi-Vala M.   +4 more
europepmc   +1 more source

Proteomic Profiling of Primary Hippocampal Neurons Reveals Noncanonical GFAP Expression and Metabolic Adaptations in Glia‐Free Culture

PROTEOMICS, EarlyView.
ABSTRACT Despite their widespread use as a research model, a comprehensive, quantitative proteomic profile of the cultured hippocampal neurons has remained unexplored. Here, we provide the first global proteomic characterization of primary murine hippocampal neurons cultured for 14 days under near‐physiological glucose conditions (2.5 mM).
Dominika Drulis‐Fajdasz, Kinga Gostomska‐Pampuch, Natalia Pudełko‐Malik, Mariusz Fleszar, Agnieszka Gizak, Jacek R. Wiśniewski, Dariusz Rakus   +6 more
wiley   +1 more source

The intake of monosodium aspartate attenuates aggression induced by post-weaning social isolation in an ADHD rat model. [PDF]

J Physiol Sci
Nishimura Y, Mustika D, Ueno S, Tominaga S, Shindo M, Tajiri N, Jung CG, Hida H.   +7 more
europepmc   +1 more source

A Gene Expression Tumor Signature Optimizing Partial Area‐Under‐the‐Curve (pAUC) to Improve Specificity for Indolent Prostate Cancer

The Prostate, EarlyView.
ABSTRACT Purpose A key clinical challenge in prostate cancer is the identification and validation of biomarkers with high specificity for indolent long‐term outcomes. We applied a novel statistical method to identify tumor transcriptomic biomarkers that optimally predicted patients with low metastatic potential.
Travis A. Gerke, Svitlana Tyekucheva, Konrad H. Stopsack, Christopher J. Sweeney, Rosina T. Lis, Elizabeth N. Westling, Massimo Loda, Meir J. Stampfer, Kathryn L. Penney, Giovanni Parmigiani, Lorelei A. Mucci   +10 more
wiley   +1 more source

A Multiple‐Model‐Informed Drug‐Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 572-582, March 2025.
ABSTRACT The antitumor efficacy of an intratumoral injection of a genetically engineered oncolytic vaccinia virus carrying human IL‐7 and murine IL‐12 genes (hIL‐7/mIL‐12‐VV) was demonstrated in CT26.WT‐bearing mice. In the CT26.WT‐bearing mouse model, the efficacy of the combination of hIL‐7/mIL‐12‐VV plus the anti‐programmed cell death protein (PD)‐1
Akihiro Yamada, Mary P. Choules, Frances A. Brightman, Shigeru Takeshita, Shinsuke Nakao, Nobuaki Amino, Takeshi Nakayama, Masato Takeuchi, Kanji Komatsu, Fernando Ortega, Hitesh Mistry, David Orrell, Christophe Chassagnole, Peter L. Bonate   +13 more
wiley   +1 more source

The acid-sensing ion channel 1a modulates anxiety- and depression-related behaviors via its influencing on the activity of corticotropin-releasing hormone-expressing neurons in the hypothalamic paraventricular nucleus in male mice. [PDF]

Transl Psychiatry
Yue J, Zhang Q, Wang M, Yao X, Wang M, Liu L, Huang Z, Xing Y, Yan J, Yan Z, Song XL, Wang W.   +11 more
europepmc   +1 more source

Modeling of Disease Progression of Type 2 Diabetes Using Real‐World Data: Quantifying Competing Risks of Morbidity and Mortality

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 606-615, March 2025.
ABSTRACT Type 2 diabetes (T2D) is a progressive metabolic disorder that could be an underlying cause of long‐term complications that increase mortality. The assessment of the probability of such events could be essential for mortality risk management. This work aimed to establish a framework for risk predictions of macrovascular complications (MVC) and
Hanna Kunina, Stefan Franzén, Maria C. Kjellsson   +2 more
wiley   +1 more source