A coordinated and enhanced brain network supports the persistence of long-term cocaine memory. [PDF]
Chen X +12 more
europepmc +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
Identification of key genes associated with muscle atrophy after spinal cord injury and experimental verification in rats. [PDF]
Wang X, Gao Y, Huo J.
europepmc +1 more source
Experimental workflow and main findings of the study. ABSTRACT Visceral pain is a major symptom of inflammatory bowel diseases (IBDs), requiring effective treatment strategies. Gut epithelium, beyond maintaining barrier integrity and microbiota homeostasis, modulates neurosensorial circuitries, influencing visceral sensitivity.
Francesco Margiotta +7 more
wiley +1 more source
Predominance of antimicrobial resistance genes and high-risk clones among Gram negatives from clinical sources in Accra-Ghana. [PDF]
Boateng W +8 more
europepmc +1 more source
The Neuroprotective Effect of a Waste Byproduct Obtained From Pomegranate (Punica granatum)
The Effect of a Waste Byproduct Obtained From Pomegranate on Neurodegeneration. ABSTRACT Pomegranate is an exceptional fruit that can have several beneficial effects on human health. The peel of pomegranate, a waste product, should be recovered as it still contains valuable constituents, including phenolic compounds, minerals and fibre. The recovery of
Jessica Maiuolo +11 more
wiley +1 more source
Dual chitosan hydrogel and polylactic acid microparticle delivery system reduces Staphylococcal osteomyelitis and soft tissue infection. [PDF]
Tucker LJ +5 more
europepmc +1 more source
Accurately estimating forest age is key to understanding how forests recover and evaluating restoration success. We developed a two‐step deep learning approach using historical greyscale aerial photographs to map forest age at fine spatial scales. By combining a pre‐trained model with localized fine‐tuning, our U‐Net + ResNet50 architecture achieved ...
Ying Ki Law +10 more
wiley +1 more source
Computed Tomography Radiomic Signatures Associated With Neutrophil Extracellular Trap Enrichment and First-Pass Outcome in Ischemic Stroke Thrombi. [PDF]
Santo BA +11 more
europepmc +1 more source
This study evaluates Ti3C2Tx MXene‐based microelectrodes across a range of diameters (25–500 µm) and elucidates their recording and stimulation capabilities for bioelectronic applications. Several electrochemical measurements—supported further by equivalent‐circuit modeling—revealed enhanced recording and stimulation capabilities of the MXene ...
Spencer R. Averbeck +6 more
wiley +1 more source

