Results 21 to 30 of about 12,144 (167)

A Modular Perfusion Bioreactor Platform for Simulating Bone Regeneration and Fracture Healing: Integrating Mechanical Loading and Dual Perfusion for Advanced In Vitro Models

Advanced Healthcare Materials, EarlyView.
A modular bioreactor platform was developed in order to replicate bone homeostasis and pathology, thereby integrating mechanical loading, dynamic perfusion, and a 3D‐printed microfluidic chamber. With precise control of environmental parameters and dual perfusion for composite tissue models, the system enhances physiological relevance for studying bone
Moritz Pfeiffenberger, Alexandra Damerau, Johannes Plank, Adel Ahmed, Mario Thiele, Jan Saam, Paula Hoff, Timo Gaber, Frank Buttgereit   +8 more
wiley   +1 more source

Biocompatible PVDF Nanofibers with Embedded Magnetite Nanodiscs Enable Wireless Magnetoelectric Stimulation in Premotor Cortex

Advanced Healthcare Materials, EarlyView.
Flexible, biocompatible PVDF nanofibers embedded with magnetite nanodiscs enable wireless magnetoelectric neuromodulation. Shape anisotropy of the nanodiscs facilitates magnetostrictive strain transfer under alternating magnetic fields, allowing activation of neurons in vitro and behavioral modulation in vivo, without requiring rigid implants or ...
Lorenzo Signorelli, Anouk Wolters, Vicente Durán Toro, Jonas Englhard, Mahdieh Shojaei Baghini, Elif Koçar, Franziska Wasner, Nadine I. Goldenstein, Hadi Heidari, Julien Bachmann, Sarah Hescham, Danijela Gregurec   +11 more
wiley   +1 more source

Advanced Electrode Materials for Efficient Hydrogen Production in Protonic Ceramic Electrolysis Cells

Advanced Materials, EarlyView.
Protonic ceramic electrolysis cells (PCECs) are a promising intermediate‐temperature hydrogen production technology, leveraging high proton conductivity in electrolytes yet constrained by insufficient catalytic activity and interfacial instability in fuel/air electrodes. This review systematically categorizes advanced electrode materials and critically
Zhipeng Liu, Lilin Zhang, Chunyue Joey Zheng, Yuan Zhang, Bin Chen, Zongping Shao, Jingjie Ge   +6 more
wiley   +1 more source

Taming Interfacial Ion‐Dipole Interactions With d‐Orbital Delocalized Electron Catalysis Expediates Low‐Temperature Li Metal Batteries

Advanced Materials, EarlyView.
The ion‐dipole interactions within Li(solvents)x+ groups for fast interfacial Li+ desolvation/diffusion and dendrite‐free deposition are reduced by taming various d‐orbital electron‐delocalized catalyzers under the low‐temperature surroundings.
Jing Zhang, Fangqi Liu, Rong He, Qinghua Guan, Na Tian, Jian Wu, Zhenjiang Cao, Shikai Yin, Yongzheng Zhang, Lujie Jia, Xifei Li, Caiyin You, Haitao Liu, Meinan Liu, Yidong Miao, Hongzhen Lin, Jian Wang   +16 more
wiley   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

Advanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton, Chris R. Bowen, Hamideh Khanbareh   +2 more
wiley   +1 more source

Wirelessly Powered Ingestible Capsule for Optical Stimulation of the Gastrointestinal Tract in Rodents

Advanced Materials Technologies, EarlyView.
An ingestible electronic capsule, ICOPS, enables non‐invasive optical gut stimulation in rodents. ICOPS features modular LEDs and optimized power transfer for robust, in vivo functionality. This cleanroom‐free, 3D‐printed platform offers a compact, scalable solution for optogenetically interfacing enteric neural circuits, promising advances in ...
Mohamed Elsherif, Rawan Badr El‐Din, Zhansaya Makhambetova, Heba Naser, Maylis Boitet, Rahul Singh, Keonghwan Oh, Revathi Sukesan, Sohmyung Ha, Khalil B. Ramadi   +9 more
wiley   +1 more source

Implantable Nongenetic Optoelectronic Biointerfaces for Neuromodulation

Advanced Photonics Research, EarlyView.
This review summarizes recent advances in semiconductor‐based optoelectronic biointerfaces for wireless, optically induced electrical neuromodulation. It highlights their diverse designs that enable precise, targeted neural modulation of cells, tissues, and organs.
Jinglin Ye, Jinwei Huang, Wenyu Nie, Jianming Xu, Xing Sheng, Huachun Wang   +5 more
wiley   +1 more source

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

Steroid Receptor Coactivator‐1 Drives Tumor‐Associated Macrophage Reprogramming by Mediating MMP12 Transcription in Pancreatic Cancer Perineural Invasion

Advanced Science, EarlyView.
Steroid receptor coactivator‐1 (SRC‐1) reprograms tumor‐associated macrophages (TAMs) via signal transducer and activator of transcription 1(STAT1)‐mediated matrix metallopeptidase 12 (MMP12) transcription to drive perineural invasion (PNI) in pancreatic cancer.
Ke Cheng, Liang Liu, Miaomiao Gong, Yuke Ji, Chunmei Bai, Xiangqian Guo, Hui Chen, Jinjin Pan, Ying Zhang, Yuhui Yuan   +9 more
wiley   +1 more source