Results 21 to 30 of about 99 (97)
Angewandte Chemie, Volume 137, Issue 20, May 12, 2025.The anti‐ and syn‐selective epoxidation of various α,β‐unsaturated aldehydes is promoted by an engineered variant of 2‐deoxy‐D‐ribose‐5‐phosphate aldolase (DERA), giving rise to various α,β‐epoxy‐aldehydes with excellent enantiopurity (enantiomeric ratio up to 99 : 1). Abstract The enzyme 2‐deoxy‐D‐ribose‐5‐phosphate aldolase (DERA) naturally catalyzes
Hangyu Zhou +5 more
wiley +2 more sources
Self‐Oscillation in Active Wires with Asymmetric Willis‐Type Viscosity
Advanced Science, EarlyView.This study suggests a self‐oscillation strategy enabled by a new set of material parameters, namely the asymmetric Willis‐type viscosity, to bias and independently control oscillation mode shapes as well as frequencies. The exemplified active wire can benefit the development of autonomous materials to construct soft motors, agitators, pumps, and ...
Xingbo Pu +3 more
wiley +1 more source
Advanced Science, EarlyView.The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park +9 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies a class of amino acid‐sensing neurons, APCCRH neurons, which regulate BAT thermogenesis. Leucine deficiency alters intrinsic excitability through GCN2 signaling pathway, activating APCCRH neurons, which in turn regulate BAT thermogenesis via projections to the lateral hypothalamus.
Peixiang Luo +15 more
wiley +1 more source
High‐Density Flexible Neural Implants with Submicron Feedline Resolution
Advanced Electronic Materials, EarlyView.Optimization of microfabrication methods using optical contact lithography (OCL) and electron beam lithography (EBL) enables the fabrication of 64‐channel, high‐density, parylene‐C‐based intracortical implants with submicron feedlines as narrow as 400 and 50 nm, respectively.
Lina Koschinski +10 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.The association between BMD reduction during NAC and the worse prognosis remains unknown, although NAC followed by esophagectomy is a standard treatment for advanced ESCC. This study appeared that BMD massive reduction was an independent prognostic factor on OS (HR, 3.30; 95% confidence interval [CI], 1.69–6.55) and RFS (HR, 2.08; 95% CI, 1.19–3.63 ...
Kazuhide Sato +11 more
wiley +1 more source
Phenobot: An Autodigital Modeling System for in situ Phenotyping in Horticulture
Advanced Intelligent Systems, EarlyView.This study introduces a robotic phenotyping system for precision agriculture, integrating environmental understanding, motion planning, and in situ plant phenotyping. The system autonomously navigates through real‐world agricultural environments, collects high‐quality plant data, and reconstructs accurate 3D plant models. Results demonstrate the system'
Kewei Hu +5 more
wiley +1 more source
Smart Transfemoral Prosthetic Socket with Motorized Cable‐Driven System
Advanced Intelligent Systems, EarlyView.This study presents an innovative transfemoral socket featuring a motorized cable‐driven system and a sensorized liner, designed to adapt to changes in residual limb volume while monitoring interface pressures. Users can seamlessly control the socket in both open‐ and closed‐loop modes via a customized mobile application, enhancing comfort and ...
Linda Paternò +7 more
wiley +1 more source
An Authentic Al=Si Double Bond
Angewandte Chemie International Edition, Volume 64, Issue 16, April 11, 2025.We report the first example of a bona fide Al=Si double bond stabilized in a four‐membered anionic AlSi3 cycle, which exhibits an unprecedentedly short Al−Si bond length of 2.283(1) Å and a high Wiberg bond index (WBI) of 1.31. We illustrate the typical double bond reactivity through the intramolecular activation of C−H bonds of the Tip group (Tip=2,4 ...
Nasrina Parvin +3 more
wiley +1 more source
Angewandte Chemie International Edition, Volume 64, Issue 20, May 12, 2025.Quenching xenon's thirst by its coordination to water in the 18‐crown‐6 complexes, [(CH2CH2O)6(H2O)XeO3] ⋅ H2O and [(CH2CH2O)6(H2O)XeO3]2⋅ 2H2O ⋅ HF, provides the first examples of Xe‐ ‐ ‐O bonded noble‐gas hydrates. These complexes, along with (CH2CH2O)4XeO3, were characterized by Raman spectroscopy, X‐ray crystallography, and computational studies ...
Katherine M. Marczenko +3 more
wiley +1 more source