Results 41 to 50 of about 11,878 (168)

Centimeter‐Scale Self‐Assembling Tendon Organoids Drive Tissue Regeneration

Advanced Science, EarlyView.
Centimeter‐scale tendon organoids are engineered by mimicking the extracellular matrix and optimizing chemical cues to guide tendon stem/progenitor cells. These large, self‐assembling constructs overcome conventional size limitations and exhibit enhanced tenogenic differentiation, extracellular matrix production, and mechanical resilience. Their tissue‐
Tianshun Fang, Hong Zhang, Yuanhao Xie, Xiongfeng Li, Xi Liu, Zichen Wang, Yiwen Xue, Xiaohui Xia, Zetao Wang, Tingyun Lei, Ruifu Lin, Weiliang Shen, Bingbing Wu, Yishan Chen, Yanan Du, Xiao Chen, Zi Yin   +16 more
wiley   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

Advanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang, Yanran Zhang, Jialin Si, Honghui Mao, Feng He, Jin Ning, Guaiguai Ma, Xiaohua Chen, Haoxiang Xiao, Yuanyuan Zhu, Haifeng Zhang, Yifan Lu, Qian Liu, Meng Nian, Shiquan Sun, Shibin Yu, Shengxi Wu, Ze Fan, Zuolin Jin, Jing Huang   +19 more
wiley   +1 more source

Hydrazine‐Mediated Thermally Assisted Photocatalytic Ammonia Decomposition Over Layered Protonated Perovskites

Advanced Science, EarlyView.
Herein, a new catalyst, protonated layered perovskite HPrNb2O7, is presented, which exhibits exceptional photocatalytic activity for solar‐driven ammonia decomposition. Its unique structure facilitates the generation of active sites while extending charge carrier lifetime with input thermal energy. Abstract Photocatalytic ammonia decomposition offers a
Haozhe Zhang, Mengqi Duan, Shuai Guo, Renzo Leeflang, Dorottya Szalay, Jiasi Li, Jo‐chi Tseng, Simson Wu, Songhua Cai, Dharmalingam Prabhakaran, Robert A. Taylor, Yiyang Li, Shik Chi Edman Tsang   +12 more
wiley   +1 more source

Tumor Microenvironment‐Responsive Nanomedicines for Potentiating Cancer Immunotherapy

Advanced Science, EarlyView.
Strategies for TME‐responsive Nanomaterials to Potentiate Cancer Immunotherapy. Abstract Immunotherapy has emerged as a transformative paradigm in oncology, yet its clinical efficacy remains constrained by the immunosuppressive tumor microenvironment and inadequate spatiotemporal control of existing modalities, resulting in suboptimal patient response ...
Qianqian Huang, Fan Tong, Jiantao Chen, Muzaffar Kayumov, Yue Lv, Yajun Shi, Bengui Ye, Huile Gao   +7 more
wiley   +1 more source

[HgX2] Linear Group Enabled Ultraviolet Birefringent Crystal RbHg5Br11 with Strong Optical Anisotropy and Wide Bandgap

Advanced Science, EarlyView.
Based on the “linear‐group” design strategy, a high performance ultraviolet birefringent material RbHg5Br11 with aligned linear [HgBr2] units, demonstrating a large birefringence (Δn ≈ 0.35@546 nm); a wide optical bandgap (≈3.73 eV); as well as a good crystal growth habit; is rationally designed; and fabricated by a simple solution method.
Yinxia Du, Wangfei Che, Yunfei Shi, Juanjuan Lu, Xiaodong Zhou, Ting Liu, Shilie Pan, Junjie Li   +7 more
wiley   +1 more source

High‐Density Flexible Neural Implants with Submicron Feedline Resolution

Advanced Electronic Materials, EarlyView.
Optimization of microfabrication methods using optical contact lithography (OCL) and electron beam lithography (EBL) enables the fabrication of 64‐channel, high‐density, parylene‐C‐based intracortical implants with submicron feedlines as narrow as 400 and 50 nm, respectively.
Lina Koschinski, Thomas Grap, Erkan Yilmaz, Marius Kleutgens, Simon Decke, Martin Kasavetov, Marie Jung, Alejandro Carnicer‐Lombarte, George Malliaras, Andreas Offenhäusser, Viviana Rincón Montes   +10 more
wiley   +1 more source

MXene‐Enhanced Electromembrane Systems for Advanced Water Applications: A Review

Advanced Energy and Sustainability Research, EarlyView.
MXenes, synthesized via etching, intercalation, and delamination, exhibit hydrophilicity, conductivity, tunability, and strength, enabling roles as membranes, electrodes, and hybrids in electrical‐driven membrane technologies. These systems leverage adsorption, catalysis, separation, and self‐cleaning but face challenges in stability, scalability ...
Zainab Alansari, Mariam Ouda, Shadi W. Hasan   +2 more
wiley   +1 more source

Smart Transfemoral Prosthetic Socket with Motorized Cable‐Driven System

Advanced Intelligent Systems, EarlyView.
This study presents an innovative transfemoral socket featuring a motorized cable‐driven system and a sensorized liner, designed to adapt to changes in residual limb volume while monitoring interface pressures. Users can seamlessly control the socket in both open‐ and closed‐loop modes via a customized mobile application, enhancing comfort and ...
Linda Paternò, Ahmed Zohaib Zaidi, Maria Grazia Polizzotto, Sofia Dalmiani, Djoeke Helsloot, Sybren Heikens, Emanuele Gruppioni, Arianna Menciassi   +7 more
wiley   +1 more source

Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases

Annals of Neurology, EarlyView.
Recapitulative schema of different exploratory levels of the evolutionary impact on human neurological diseases. Clinical neuroscience focuses on the mechanisms of brain function, but this approach falls short of insights into how the central nervous system (CNS) evolved, both in health and disease.
Nico J. Diederich, Martin Brüne, John S. Allen, Nicole Bender, Emiliano Bruner, Jean‐Pierre Changeux, Corrado Cali, Olga Dolgova, Anne Grünewald, Geneviève Konopka, Peng Jin, Roger Lemon, Gilberto Levy, Pierre Magistretti, Markus J. Rantala, Kathleen S. Rockland, Roger Sullivan, Annie Swanepoel, Toshiki Uchihara, Katrin Amunts, Christopher G. Goetz   +20 more
wiley   +1 more source

Fractional‐order controller tuning via minimization of integral of time‐weighted absolute error without multiple closed‐loop tests

Asian Journal of Control, EarlyView.
Abstract This study presents a non‐iterative tuning technique for a linear fractional‐order (FO) controller, based on the integral of the time‐weighted absolute error (ITAE) criterion. Minimizing the ITAE is a traditional approach for tuning FO controllers. This technique reduces the over/undershoot and suppresses the steady‐state error. In contrast to
Ansei Yonezawa, Heisei Yonezawa, Shuichi Yahagi, Itsuro Kajiwara, Shinya Kijimoto   +4 more
wiley   +1 more source