Results 61 to 70 of about 13,161 (166)

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva, Monique Mantovani, Maria E. S. D. Lino, Aline O. Albuquerque, João H. M. da Silva, Ronaldo A. P. Nagem, Adriana L. Rojas, Geraldo R. Sartori, Eduardo Horjales, David Campbell, Otavio H. Thiemann   +10 more
wiley   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

A new criterion for defining tunnel portal failure using the strength reduction method. [PDF]

PLoS One
Hua C, Zhang H, Song C, Yao L.
europepmc   +1 more source

The Neuroprotective Effect of a Waste Byproduct Obtained From Pomegranate (Punica granatum)

Phytotherapy Research, EarlyView.
The Effect of a Waste Byproduct Obtained From Pomegranate on Neurodegeneration. ABSTRACT Pomegranate is an exceptional fruit that can have several beneficial effects on human health. The peel of pomegranate, a waste product, should be recovered as it still contains valuable constituents, including phenolic compounds, minerals and fibre. The recovery of
Jessica Maiuolo, Valeria Mazza, Rosamaria Caminiti, Francesca Oppedisano, Saverio Nucera, Salvatore Ragusa, Sara Ilari, Lucia Carmela Passacatini, Luigi Tucci, Giuseppe Trunfio, Vincenzo Mollace, Carolina Muscoli   +11 more
wiley   +1 more source

Nut Consumption and Long-Term Risk of All-Cause Dementia: Preliminary Findings from Three Prospective Cohort Studies. [PDF]

Nutrients
Zhao M, Yan M, Fei L, Chen H, Wu M, Li Y, Huang L, Shen J, Liu G, Guasch-Ferré M, Salas-Salvadó J, Yuan C.   +11 more
europepmc   +1 more source

Agrivoltaic Lettuce Production Under Future Climates: A Sustainable Strategy for Optimizing Food and Energy Yields

Sustainable Development, EarlyView.
ABSTRACT Food system resilience is increasingly challenged by climate change and global trade volatility, even in high‐income nations like Canada. Agrivoltaics—co‐locating crops and photovoltaics (PV)–offers a sustainable production strategy to optimize land use and address both food and energy security.
Uzair Jamil, Linda Alrayes, Eric Fordjour, Raymond Thomas, Joshua M. Pearce   +4 more
wiley   +1 more source

FOS drives podocyte injury and renal fibrosis in diabetic kidney disease via direct Smad3 binding. [PDF]

Cell Mol Life Sci
Sun M, Yan T, Zhao W, Cheng Z.
europepmc   +1 more source

Acid Resistant and Highly Silver Selective Membranes Based on Charged Nanoporous 2D‐Materials

Small, EarlyView.
In this work, new membranes based on charged & nanoporous nanosheets with unprecedented selectivity to silver versus a wide range of other metallic ions are reported. Furthermore, a demonstrated and lead specific intralamellar lead pathway is demonstrated. A potential applicability for ubiquitous silver in WEEE is validated.
Sarah M. Chevrier, Thibault Rosier, Bo Han, Lina Cherni, Fabien L. Olivier, Hélène Isnard, Jean‐Christophe P. Gabriel   +6 more
wiley   +1 more source

Prebiotic Potential of Oligosaccharides and Polysaccharides Extracted from <i>Leucaena leucocephala</i> Seeds. [PDF]

Foods
Almeida VDSS, Mendes AGG, Campos CDL, Wolff LAS, Fontes AJC, Pereira-Filho JL, Costa TF, Monteiro CRAV, de Menezes AS, Vélez HAV, Viana KDAL, Monteiro-Neto V.   +11 more
europepmc   +1 more source