Results 11 to 20 of about 5,265 (113)

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source

Astrocytic FDX1 Contributes to Copper Dyshomeostasis‐associated Synaptic Dysfunction in Depression and Is Modulated by Exercise

Advanced Science, EarlyView.
Chronic stress disrupts copper homeostasis and promotes copper accumulation in the prelimbic cortex, leading to astrocytic FDX1 upregulation. Elevated astrocytic FDX1 impairs calcium signaling, induces structural atrophy, and disrupts synaptic function, contributing to depressive‐like behaviors. Physical exercise reverses these alterations by restoring
Lina Gao, Rongji Hui, Zhibo Tang, Tao Feng, Zhihang Hu, Xiaoqing Zhang, Ping Jiang, Hui Zhao, Kwok‐Fai So, Tianyuan Luo, Yanzhou Chang, Lan Yan   +11 more
wiley   +1 more source

An Anterior Cingulate Cortex‐Anterior Insular Cortex Glutamatergic Circuit Gates Stress‐Induced Visceral Hypersensitivity and Anxiety via Ionotropic Glutamate Receptors Trafficking

Advanced Science, EarlyView.
This study identifies an anterior cingulate cortex (ACC) to anterior insular cortex (AIC) glutamatergic (Glu) circuit that gates stress induced visceral hypersensitivity and anxiety. Circuit activation induces both phenotypes, whereas inhibition relieves them.
Junwen Wang, Guangbing Duan, Huihui Sun, Zhiyu Dong, Qiwei Wang, Xiaowei Li, Ying Chen, Shuchang Xu, Ying Huang   +8 more
wiley   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Sustainability Assessment of Micro, Small, and Medium Enterprises: A Systematic Review and Hybrid Architecture for Credible, Salient, and Legitimate Knowledge Governance

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Sustainability assessment advances corporate social responsibility toward inclusive development. Widely recognized approaches prove inadequate for micro, small, and medium enterprises (MSMEs), resulting in fragmented proliferation that hinders cumulative knowledge.
Luísa Couto Gonçalves de Souza, Laura Proença Guimarães, Maria Auxiliadora Drumond   +2 more
wiley   +1 more source

Daily Associations Between Perceived Maternal Privacy Invasion and Youth Information Management: How Do Cultural Factors Matter?

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Perceptions of parental privacy invasion can predict increased youth concealment across monthly and yearly timescales. However, daily associations between parental privacy invasion and youth information management may differ from patterns widely examined at broader measurement intervals, with cultural values potentially shaping ...
Dan Gao, Yue Wang, Skyler T. Hawk
wiley   +1 more source

An Inferential‐Based Model of Scrupulosity and Obsessive–Compulsive Disorder Across Cultures: The Roles of Fear of Self and Obsessive Beliefs

Journal of Clinical Psychology, EarlyView.
ABSTRACT Although inferential confusion (IC), fear of self (FOS), and obsessive beliefs have each been linked to obsessive–compulsive disorder (OCD), they have rarely been examined together within the inferential‐based approach (IBA) or considered across different cultural contexts. This study examined a cross‐sectional model in which IC was associated
Mujgan Inozu, Nicholas S. Myers, Özlem Ergin Ayan, Yasemin Erol, Elif Usta, Elif Uzumcu, Joseph B. Friedman, Emily K. Juel, Jonathan S. Abramowitz   +8 more
wiley   +1 more source

The Edification of Manuela Xiqués: Slavery, Finance, Biography, and the Construction of Modern Barcelona

Gender &History, EarlyView.
ABSTRACT An analysis of the dual biographies, economic and domestic, of Manuela Xiqués, an enslaver from nineteenth‐century Cuba and Spain, deepens our understanding of the role of European and Creole women in the nineteenth‐century Atlantic. This essay foregrounds the role of literature, namely family biography, as a locus of the processes of ...
Lisa Surwillo, Martín Rodrigo Alharilla
wiley   +1 more source

‘Mere Amateurs’? Elementary Teachers and the Making of Scientific Authority in the British Child Study Movement

History, EarlyView.
Abstract This article offers new perspectives on the relationship between elementary teaching, scientific expertise and the professionalization of the human sciences. Previous scholarship has demonstrated the ready existence of ‘amateur’ science societies in the nineteenth century where cross‐class exchanges were common.
Julia Gustavsson
wiley   +1 more source

Sino‐Mexican Encounters Before the ‘Diplomatic Opening’: Exhibition Diplomacy and Grassroots Friendship in the 1960s

History, EarlyView.
Abstract During the 1960s, Mexico's Institutional Revolutionary Party (PRI) embraced Chinese overtures for a commercial opening as consistent with its anti‐imperialist posture, thereby foreshadowing the diplomatic opening to China in 1972. Yet this professed ideological pluralism was eclipsed by an underlying allegiance to the United States' anti ...
YIXIN TIAN
wiley   +1 more source