Results 31 to 40 of about 5,265 (113)

Gut microbiota‐targeted interventions for depression in adolescents and young adults: Mechanisms, evidence strength and clinical strategies—A narrative review

General Psychiatry, Volume 39, Issue 4, August 2026.
ABSTRACT Depression in adolescents and young adults is common, associated with substantial functional impairment and characterised by limited treatment efficacy. The microbiota–gut–brain (MGB) axis has emerged as a potential therapeutic target for depression.
Hanchen Hou, Yinan Li, Wanting Tang, Yiwen Gao, Yuanyuan Tian, Fei Chen, Lige Zhang, Jushuang Zhang, Xiaoxia Xu, Yao Li, Yi Li, Qingshan Wang, Lingli Liu, Teng Teng, Hao Wu, Xinyu Zhou   +15 more
wiley   +1 more source

Application of Population‐Based Meta‐Heuristic Algorithms for Robust Initialization in Mechanistic Pharmacometric Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.
ABSTRACT Mechanistic PK/PD models represent complex biological systems in which model parameters are in nonlinear, multidimensional parameter spaces and often require robust optimization informed by experimental data, making parameter estimation a critical yet challenging aspect of pharmacometric analysis.
Dongjin Lee, Chih‐Wei Lin
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, Volume 40, Issue 8, Page 4759-4791, August 2026.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Value and moral divergences between management researchers and managers: Evidence and a future research agenda

Applied Psychology, Volume 75, Issue 4, August 2026.
Abstract We know little about the values and morals that management researchers hold and whether they align with a key set of stakeholders they intend to inform—managers in industry. This alignment matters because values and morals serve as guiding principles and are important drivers of attitudes and behavior, and differences in values and morals can ...
Jake B. Telkamp, Marc H. Anderson
wiley   +1 more source

Understanding the Link Between Social Support Networks, Self‐Efficacy and Future Orientation During Emerging Adulthood: A Comparison of At‐Risk and Non‐at‐Risk Emerging Adults

Child &Family Social Work, Volume 31, Issue 3, Page 1664-1675, August 2026.
ABSTRACT At‐risk emerging adults may be less inclined to invest in future goals, yet the mechanisms underlying their future orientation (FO) remain unclear. Therefore, this study examined how social support network attributes contribute to FO in at‐risk and non‐at‐risk emerging adults and the mediating role of self‐efficacy.
Eran P. Melkman, Yafit Sulimani‐Aidan
wiley   +1 more source

Partisan Entrepreneurship

The Journal of Finance, Volume 81, Issue 4, Page 1841-1892, August 2026.
ABSTRACT Republicans start more firms than Democrats. In a sample of 40 million party‐identified Americans between 2005 and 2017, we find that 5.5% of Republicans and 3.7% of Democrats become entrepreneurs. This partisan entrepreneurship gap is time‐varying—Republicans increase their relative entrepreneurship during Republican administrations and ...
JOSEPH ENGELBERG, JORGE GUZMAN, RUNJING LU, WILLIAM MULLINS   +3 more
wiley   +1 more source

Object location memories recruit distal CA1 and catecholaminergic inputs to proximodistal CA1. [PDF]

PLoS One
Crestani AP, Teratani-Ota Y, Wiltgen BJ.
europepmc   +1 more source

The role of nucleus accumbens Fos expression in sex-dependent cocaine-induced locomotion, cocaine self-administration, and primed cocaine seeking in rats. [PDF]

Behav Brain Res
Mascarin AT, Kallakuri S, Carthage JL, Gheidi A, Conti AC, Perrine SA.   +5 more
europepmc   +1 more source

Adaptations to cognitive behavioral therapy for insomnia to address fear of sleep and its sequential impact on posttraumatic stress disorder following cognitive processing therapy. [PDF]

Sleep Adv
Pigeon WR, Youngren WA, Crean HF, Staples VW, Bishop TM, Cerulli C, Gallegos AM, Heffner KL.   +7 more
europepmc   +1 more source

Hedonic hotspot in rat olfactory tubercle: map for mu-opioid, orexin, and muscimol enhancement of sucrose 'liking'. [PDF]

Neuropsychopharmacology
Murata K, Berridge KC.
europepmc   +1 more source