Results 31 to 40 of about 4,688 (101)

The Efficacy of Intravenous Analgesia and Various Nerve Blocks for Pain Management in Elderly Patients With Hip Fractures: A Meta‐Analysis

Orthopaedic Surgery, EarlyView.
Nerve blocks significantly improve pain management, reduce opioid consumption, and lower adverse reactions compared to intravenous analgesia in elderly patients with hip fractures. ABSTRACT Pain management in elderly patients with hip fractures has received more and more attention, which is crucial for promoting recovery and reducing complications.
Yuping Liu, Li Zhou, Xin Wang
wiley   +1 more source

Orexinergic neurons contribute to autonomic cardiovascular regulation for locomotor exercise

The Journal of Physiology, EarlyView.
Abstract figure legend This study unveiled the essential role of the orexinergic nervous system in the central circuitry that transmits central command signals for locomotor exercise. We observed the excitation of orexinergic neurons by voluntary locomotor exercise in rats.
Emi Narai, Yuki Yoshimura, Takaho Honaga, Hiroyuki Mizoguchi, Akihiro Yamanaka, Takeshi Y. Hiyama, Tatsuo Watanabe, Satoshi Koba   +7 more
wiley   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

The Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas, Patricia Pelufo Silveira   +1 more
wiley   +1 more source

Human brain imaging with high‐density electroencephalography: Techniques and applications

The Journal of Physiology, EarlyView.
Abstract figure legend Recent technological advances have elevated high‐density electroencephalography (hdEEG) to the status of a reliable neuroimaging tool. This technique measures scalp potentials with high temporal resolution, which permits the non‐invasive detection and analysis of neural oscillations.
Marco Marino, Dante Mantini
wiley   +1 more source

The Role of Peripheral N‐Methyl‐D‐Asparate (NMDA) Receptors in Itch and Pain: A Narrative Review

European Journal of Pain, Volume 29, Issue 7, August 2025.
ABSTRACT Background and Objective NMDA receptors, predominantly located in the central nervous system and known for their roles in synaptic plasticity and central sensitisation of pain and itch, are also expressed in peripheral sensory neurons. Emerging evidence suggests that peripheral NMDA receptors contribute to pathological pain and potentially ...
Ryusuke Tanaka, Silvia Lo Vecchio, Giulia Erica Aliotta, Lars Arendt‐Nielsen   +3 more
wiley   +1 more source

ESPGHAN/NASPGHAN guidelines for treatment of irritable bowel syndrome and functional abdominal pain‐not otherwise specified in children aged 4–18 years

Journal of Pediatric Gastroenterology and Nutrition, Volume 81, Issue 2, Page 442-471, August 2025.
Abstract Objectives Abdominal pain related disorders of gut–brain interaction (AP‐DGBIs) such as irritable bowel syndrome (IBS) and functional abdominal pain‐not otherwise specified (FAP) are common conditions in children, significantly impacting quality of life.
Jip Groen, Morris Gordon, Ashish Chogle, Marc Benninga, Rachel Borlack, Osvaldo Borrelli, Anil Darbari, Jernej Dolinsek, Julie Khlevner, Carlo Di Lorenzo, Hannibal Person, Rinarani Sanghavi, Julie Snyder, Nikhil Thapar, Arine Vlieger, Vasiliki Sinopoulou, Merit Tabbers, Miguel Saps   +17 more
wiley   +1 more source

Effects of microbiota‐based interventions on depression and anxiety in children and adolescents—A systematic review

Journal of Pediatric Gastroenterology and Nutrition, Volume 81, Issue 2, Page 404-416, August 2025.
Abstract This study aims to systematically review evidence on gut microbiota‐based interventions for reducing depression‐ and anxiety‐like symptoms in children and adolescents with autism spectrum disorder, irritable bowel syndrome, Prader‐Willi syndrome, below‐average literacy skills or anorexia nervosa, where some individuals may exhibit indicators ...
Jiayu Hu, Yan Zhang, Chuwen Liu, Antigone Gkaravella, Jinyue Yu   +4 more
wiley   +1 more source

Macrophages: Subtypes, Distribution, Polarization, Immunomodulatory Functions, and Therapeutics

MedComm, Volume 6, Issue 8, August 2025.
Macrophages originate from the yolk sac, fetal liver, and bone marrow, differentiating into two main subtypes: M1‐like (proinflammatory) and M2‐like (anti‐inflammatory). These subtypes exhibit high plasticity, allowing them to transform in response to environmental cues or therapeutic interventions.
Mengyuan Peng, Niannian Li, Hongbo Wang, Yaxu Li, Hui Liu, Yanhua Luo, Bao Lang, Weihang Zhang, Shilong Li, Liujun Tian, Bin Liu   +10 more
wiley   +1 more source

Making Sense of Erotically Oppressive Lifeworlds: Dynamics of Testimonial Smothering and Testimonial Quieting

Journal of Social Philosophy, EarlyView.
Paul Giladi
wiley   +1 more source

Psilocybin as Transformative Fast‐Acting Antidepressant: Pharmacological Properties and Molecular Mechanisms

Fundamental &Clinical Pharmacology, Volume 39, Issue 4, August 2025.
ABSTRACT In the 1950s–60s, serotonergic psychedelic drugs were studied as potential adjuvants to psychotherapy to treat addiction and alcoholism. However, starting in the 70s, preclinical and clinical studies on psychedelics stopped for decades because legislation controlled its recreational use, citing their hallucinogenic and psychotomimetic effects,
Makiath Adebo, Mathilda Bonnet, Ons Laouej, Celine Defaix, Josephine C. McGowan, Florence Butlen‐Ducuing, Denis J. David, Erwan Poupon, Laurent Tritschler, Alain M. Gardier   +9 more
wiley   +1 more source