Results 131 to 140 of about 36,369 (248)

In vitro fosfomycin study on concordance of susceptibility testing methods against ESBL and carbapenem-resistant Enterobacteriaceae

Journal of Global Antimicrobial Resistance, 2020
Objectives: The increasing emergence and diffusion of multidrug-resistant (MDR) pathogenic bacteria, both in hospital and community settings, is inducing clinicians to reconsider old antibiotics, such as fosfomycin, to overcome the difficulties posed by ...
Ausilia Aprile, Guido Scalia, Stefania Stefani, Maria Lina Mezzatesta   +3 more
doaj   +1 more source

The Role of Bacillithiol in Gram-Positive Firmicutes [PDF]

, 2018
Significance: Since the discovery and structural characterization of bacillithiol (BSH), the biochemical functions of BSH-biosynthesis enzymes (BshA/B/C) and BSH-dependent detoxification enzymes (FosB, Bst, GlxA/B) have been explored in Bacillus and ...
Antelmann, Haike, Chandrangsu, Pete, Helmann, John D., Loi, Vu Van   +3 more
core   +1 more source

Effect of 5-Day Nitrofurantoin vs Single-Dose Fosfomycin on Clinical Resolution of Uncomplicated Lower Urinary Tract Infection in Women: A Randomized Clinical Trial

Journal of the American Medical Association (JAMA), 2018
Importance The use of nitrofurantoin and fosfomycin has increased since guidelines began recommending them as first-line therapy for lower urinary tract infection (UTI).
A. Huttner, A. Kowalczyk, A. Turjeman, T. Babich, Caroline Brossier, N. Eliakim‐Raz, Katarzyna Kosiek, B. Martinez de Tejada, X. Roux, Shachaf Shiber, U. Theuretzbacher, E. von Dach, D. Yahav, L. Leibovici, M. Godycki-Cwirko, J. Mouton, S. Harbarth   +16 more
semanticscholar   +1 more source

Assessing the Genomic Landscape of Salmonella enterica Isolated From Cattle Faeces on a Nigerian Farm

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
This study examined Salmonella enterica isolated from cattle faeces on a Nigerian farm. All isolates exhibited complete susceptibility to tested antibiotics, and whole‐genome sequencing revealed minimal antimicrobial resistance gene carriage. These findings demonstrate a notably low resistance burden which is an uncommon observation in many low‐and ...
Adewale A. Adetoye, Ayorinde O. Afolayan, Olabisi C. Akinlabi, Stella E. Ekpo, Isaac O. Olatoye, Funmilola A. Ayeni   +5 more
wiley   +1 more source

Efficacy of high doses of intravenous fosfomycin for treatment of urinary tract infection caused by KPC carbapenemase-producing Klebsiella pneumoniae: An observational study

Journal of Global Antimicrobial Resistance
: Objective: To evaluate the efficacy of high-dose intravenous fosfomycin for the treatment of urinary tract infections (UTI) caused by KPC carbapenemase-producing Klebsiella pneumoniae (KPC-Kp).
Jorge Rodríguez-Gómez, Irene Gracia-Ahufinger I, Rosario Carmona-Flores, Julia Guzmán-Puche, Rafael León, Elena Pérez-Nadales, Monserrat Muñoz de la Rosa, Alejandra Mendez Natera, Juan José Castón, Ángela Cano, Juan Jesús Pineda-Capitán, Cristina López, Carmen De la Fuente-Martos, Julián Torre-Cisneros, Luis Martínez-Martínez   +14 more
doaj   +1 more source

Antimicrobial susceptibilities of clinical bacterial isolates from urinary tract infections to fosfomycin and comparator antibiotics determined by agar dilution method and automated micro broth dilution

Microbiology Spectrum
Uncomplicated bacteremic urinary tract infections (bUTIs) are common, often caused by Escherichia coli, Klebsiella pneumoniae, and Enterococcus faecalis, with most encounters treated empirically.
Jamie L. Dombach, Nancy C. Smith, Teresa Kottiri, Alicia M. Schiller, Edwin Kamau   +4 more
doaj   +1 more source

Characterization of fosS, a novel fosfomycin-modifying enzyme gene identified in Staphylococcus haemolyticus

One Health Advances
The efficacy of fosfomycin is increasingly challenged by emerging resistance mechanisms, primarily involving fosfomycin-modifying enzymes and target (MurA) alterations. This study aimed to elucidate the novel mechanism underlying fosfomycin resistance in
Honghao Huang, Huan Chen, Ruonan Zhao, Yiyi Chen, Jianxin Hu, Peng Wan, Lingxuan Zhang, Wengaung Xiong, Yan Chen, Yafei Li, Zhenling Zeng   +10 more
doaj   +1 more source

Evaluating Prescriber Adherence to Guideline-Based Treatment Pathways of a Newly Initiated Antimicrobial Stewardship Program at a Rehabilitation Hospital [PDF]

, 2017
Background: Inappropriate use of antimicrobials in the healthcare setting is associated with consequences including antimicrobial resistance, Clostridium difficile infection (CDI), adverse drug reactions, and increased healthcare costs.
Bertram, Christie
core   +1 more source

Discovery of chlamydial peptidoglycan reveals bacteria with murein sacculi but without FtsZ [PDF]

, 2013
Chlamydiae are important pathogens and symbionts with unique cell biological features. They lack the cell-division protein FtsZ, and the existence of peptidoglycan (PG) in their cell wall has been highly controversial.
Aistleitner, Karin, Biboy, Jacob, Brun, Yves V., Gray, Joe, Hall, Edward, Horn, Matthias, Jensen, Grant J., Kuru, Erkin, Pilhofer, Martin, VanNieuwenhze, Michael S., Vollmer, Waldemar   +10 more
core   +2 more sources

The erratic antibiotic susceptibility patterns of bacterial pathogens causing urinary tract infections [PDF]

, 2015
Increasing trend of antibiotic resistance and expression of Extended Spectrum Beta Lactamases (ESBLs) are serious threats for public health as they render the treatment ineffective.
Ahmed, Iftkhar, Anees, Mariam, Maqsood, Bushra, Murtaza, Iram, Sajed, Muhammad, Sultan, Aneesa, Vanhara, Petr, Yousaf, Sohail   +7 more
core   +1 more source