Fosinopril mediates antitumor efficacy by inducing GSDME-dependent pyroptosis in NSCLC [PDF]
Repurposing existing drugs offers a promising approach to cancer therapy. Fosinopril, an angiotensin converting enzyme inhibitor (ACEI) approved for hypertension, has demonstrated antitumor effects in hepatocellular carcinoma.
Yue Gao +10 more
doaj +2 more sources
ACE inhibitor fosinopril in the treatment of hypertension: potential benefits
Fosinopril with dual clearance can be used in renal failure without dose correction, which may be required in diabetes or elderly patients even with normal creatinine level in blood plasma.
AO Konradi
doaj +2 more sources
Efficacy of fosinopril and amlodipine in pediatric primary hypertension: a single-center observational study [PDF]
ObjectiveFosinopril and amlodipine are commonly prescribed as first-line pharmacotherapeutic agents for pediatric hypertension, but there is a lack of comparative studies regarding the efficacy of these two drugs.
Hui Wang +6 more
doaj +2 more sources
EFFECTS OF AMLODIPINE, FOSINOPRIL AND METOPROLOL ON HEMODYNAMICS IN HYPERTENSIVE PATIENTS
Aim. To assess an efficacy of antihypertensive therapy with calcium antagonist, angiotensin converting enzyme inhibitor and β-blocker in patients with arterial hypertension (AH) taking into account influence on central and peripheral hemodynamics ...
A. L. Hohlov +4 more
doaj +5 more sources
Fosinopril inhibits Ang II-induced VSMC proliferation, phenotype transformation, migration, and oxidative stress through the TGF-β1/Smad signaling pathway [PDF]
Fosinopril (FOS) is an angiotensin-converting enzyme inhibitor that can decrease angiotensin II (Ang II) formation, thereby reducing systemic vasoconstriction.
Chen Siqi, Ye Lingxiang
doaj +2 more sources
Clinical case: the experience of using acetylsalicylic acid, fosinopril and diltiazem in the therapy of a patient with cardiovascular pathology [PDF]
The article briefly describes the inhibitor of angiotensin converting enzyme (ACEI) - fosinopril, calcium channel blocker - diltiazem and antiplatelet agent- acetylsalicylic acid (ASA).
V. S Zadionchenko +6 more
doaj +1 more source
Hyperkalemia in hypertensive patients undergoing regular hemodialysis during enalapril and fosinopril therapy [PDF]
Introduction. Hypertension is evident in 80%-85% of patients with chronic renal failure and antihypertensive therapy is needed in 25%-30% of patients. Apart from antihypertensive effect, ACEi’s decrease the left ventricular hypertrophy and mortality in ...
Dimković Nada +7 more
doaj +1 more source
Background Plasma fibroblast growth factor 23 (FGF23) has been reported to be a predictive biomarker for therapeutic effectiveness of angiotensin‐converting enzyme inhibitors in heart failure.
Yao Lin +7 more
doaj +1 more source
Aim. To study dynamics of the indices of heart rate variability (HRV) and heart remodeling in response on combined therapy with fosinopril and simvastatin in postmenopausal metabolic syndrome (MS). Material and methods. 95 women were dynamically examined
I. V. Logacheva +2 more
doaj +1 more source

