Fosinopril mediates antitumor efficacy by inducing GSDME-dependent pyroptosis in NSCLC [PDF]
Cell Death DiscoveryRepurposing existing drugs offers a promising approach to cancer therapy. Fosinopril, an angiotensin converting enzyme inhibitor (ACEI) approved for hypertension, has demonstrated antitumor effects in hepatocellular carcinoma.
Yue Gao +10 more
doaj +2 more sources
Efficacy of fosinopril and amlodipine in pediatric primary hypertension: a single-center observational study [PDF]
Frontiers in Pediatrics, 2023 ObjectiveFosinopril and amlodipine are commonly prescribed as first-line pharmacotherapeutic agents for pediatric hypertension, but there is a lack of comparative studies regarding the efficacy of these two drugs.
Hui Wang +6 more
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Exploring the disruption of SARS-CoV-2 RBD binding to hACE2 [PDF]
Frontiers in Chemistry, 2023 The COVID-19 pandemic was declared due to the spread of the novel coronavirus, SARS-CoV-2. Viral infection is caused by the interaction between the SARS-CoV-2 receptor binding domain (RBD) and the human ACE2 receptor (hACE2).
Camryn Carter +4 more
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Fosinopril inhibits Ang II-induced VSMC proliferation, phenotype transformation, migration, and oxidative stress through the TGF-β1/Smad signaling pathway [PDF]
Open Life SciencesFosinopril (FOS) is an angiotensin-converting enzyme inhibitor that can decrease angiotensin II (Ang II) formation, thereby reducing systemic vasoconstriction.
Chen Siqi, Ye Lingxiang
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Clinical case: the experience of using acetylsalicylic acid, fosinopril and diltiazem in the therapy of a patient with cardiovascular pathology [PDF]
КардиоСоматика, 2018 The article briefly describes the inhibitor of angiotensin converting enzyme (ACEI) - fosinopril, calcium channel blocker - diltiazem and antiplatelet agent- acetylsalicylic acid (ASA).
V. S Zadionchenko +6 more
doaj +1 more source
EFFECTS OF AMLODIPINE, FOSINOPRIL AND METOPROLOL ON HEMODYNAMICS IN HYPERTENSIVE PATIENTS
Рациональная фармакотерапия в кардиологии, 2015 Aim. To assess an efficacy of antihypertensive therapy with calcium antagonist, angiotensin converting enzyme inhibitor and β-blocker in patients with arterial hypertension (AH) taking into account influence on central and peripheral hemodynamics ...
A. L. Hohlov +4 more
doaj +3 more sources
The toxicity of angiotensin converting enzyme inhibitors to larvae of the disease vectors Aedes aegypti and Anopheles gambiae [PDF]
, 2017 The control of mosquitoes is threatened by the appearance of insecticide resistance and therefore new control chemicals are urgently required. Here we show that inhibitors of mosquito peptidyl dipeptidase, a peptidase related to mammalian angiotensin ...
A Enayati +54 more
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Hyperkalemia in hypertensive patients undergoing regular hemodialysis during enalapril and fosinopril therapy [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2006 Introduction. Hypertension is evident in 80%-85% of patients with chronic renal failure and antihypertensive therapy is needed in 25%-30% of patients. Apart from antihypertensive effect, ACEi’s decrease the left ventricular hypertrophy and mortality in ...
Dimković Nada +7 more
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Plasma fibroblast growth factor 23 (FGF23) has been reported to be a predictive biomarker for therapeutic effectiveness of angiotensin‐converting enzyme inhibitors in heart failure.
Yao Lin +7 more
doaj +1 more source