Results 11 to 20 of about 180 (132)

Effect of Tangshen formula on alleviating oxidative renal injury in UUO mice by downregulated expression of NADPH oxidase

open access: yesJournal of Radiation Research and Applied Sciences, 2022
Objective: To explore the effect of Tangshen formula on the oxidative renal injury in UUO mice. Method: Seven-week-old male mice C57BL/6N were selected and randomly divided into sham-surgery group, UUO model group (UUO-7d and UUO-14d), Tangshen formula ...
Xinyu Ding   +8 more
doaj   +1 more source

THE DYNAMICS OF 0,1 HZ-COMPONENT OF HEART RATE VARIABILITY AT PATIENTS WITH ARTERIAL HYPERTENSION AT TREATMENT BY FOSINOPRIL AND ATENOLOL [PDF]

open access: yesСаратовский научно-медицинский журнал, 2008
Aim: to study dynamics of the 0,1Hz-componentofthe heart rate variability(HRV) spectrum in patients with arterial hypertension taking fosinopril and atenolol. 49 patients with hypertension were enrolled (age - 46+/-7 years).
A.N. Strunina   +5 more
doaj  

Application of PNR Detection in the Diagnosis and Drug-efficacy Evaluation of Diabetic Kidney Disease in Rats

open access: yesShiyan dongwu yu bijiao yixue
Objective This study aims to monitor the mRNA ratio of podocin to nephrin (PNR) in glomerular podocytes of early diabetic kidney disease (DKD) rat models. The feasibility of using PNR as an early diagnostic indicator for DKD was evaluated by comparing it
ZHANG Naiqun   +4 more
doaj   +1 more source

Development and validation of a UV-spectrophotometric method for determination of an ACE inhibitor in pharmaceutical formulations [PDF]

open access: yesFolia Medica
Introduction: Fosinopril sodium, an angiotensin-converting enzyme inhibitor, is a widely prescribed antihypertensive agent and one of the leading drugs approved for use in hypertension management.
Yana Gvozdeva
doaj   +3 more sources

Aliskiren, Fosinopril, and Their Outcome on Renin-Angiotensin-Aldosterone System (RAAS) in Rats with Thyroid Dysfunction

open access: yesInternational Journal of Endocrinology, 2019
Background and Objectives. Thyroid hormones have an important role in the growth and development of various tissues including the kidney, which is the major site of renin release and the consequent angiotensin and aldosterone formation.
Susan A. S. Farhadi, Kawa F. Dizaye
doaj   +1 more source

Comparative Effect of Lisinopril and Fosinopril in Mitigating Learning and Memory Deficit in Scopolamine-Induced Amnesic Rats

open access: yesAdvances in Pharmacological Sciences, 2015
Lisinopril and fosinopril were compared on scopolamine-induced learning and memory deficits in rats. A total of eighty-four male Wistar rats were divided into seven groups.
Debasree Deb   +3 more
doaj   +1 more source

Impact of Prior Angiotensin‐Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker Use on Delirium Incidence in ICU Patients: A Retrospective Study

open access: yesHealth Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims This investigation aimed at exploring the impact that the pre‐existing use of angiotensin‐converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) has on the incidence of delirium in patients within the intensive care unit (ICU).
Zhe Li   +4 more
wiley   +1 more source

Fosinopril mediates antitumor efficacy by inducing GSDME-dependent pyroptosis in NSCLC

open access: yesCell Death Discovery
Repurposing existing drugs offers a promising approach to cancer therapy. Fosinopril, an angiotensin converting enzyme inhibitor (ACEI) approved for hypertension, has demonstrated antitumor effects in hepatocellular carcinoma.
Yue Gao   +10 more
doaj   +1 more source

Choosing antihypertensive drug for the treatment of hypertension

open access: yesМедицинский совет, 2013
The article tells about modern approaches to differentiated choice of antihypertensive drugs. The advantages and limitations of five key classes of antihypertensive medications are described.
O. D. Ostroumova, I. I. Kopchyonov
doaj   +1 more source

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi   +6 more
wiley   +1 more source

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