Linking FHIR-Based Medication Data to a Computable Algorithm for Heart Medication Optimization: A Critical Component of Any Medication Learning Health System. [PDF]
Learn Health SystABSTRACT Introduction Despite strong evidence supporting guideline‐directed medical therapy (GDMT) for heart failure with reduced ejection fraction (HFrEF), a significant gap persists in the consistent application of these therapies. This shortfall has prompted organizations like the American College of Cardiology to recommend leveraging electronic ...
LeGrand J +5 more
europepmc +2 more sources
Utilization and Dose Optimization of Angiotensin-Converting Enzyme Inhibitors in Heart Failure Patients With Reduced Ejection Fraction: A Cross Sectional Study on Implications for Guideline-Targeted Therapy. [PDF]
Health Sci RepABSTRACT Background and Aims Angiotensin‐converting enzyme inhibitors (ACEIs) are well established in reducing morbidity and mortality among patients with chronic heart failure (CHF). Evidence has consistently supported the use of high‐dose ACEI therapy, which is recommended to optimize clinical outcomes and enhance patients' quality of life ...
Kampamba M +5 more
europepmc +2 more sources
Angiotensinogen II Receptor Blockers May Decrease Risk of Adhesive Capsulitis After Rotator Cuff Repair. [PDF]
Arthrosc Sports Med RehabilPurpose To determine the effect of commonly prescribed antifibrotic medications on the odds of developing adhesive capsulitis (AC) following arthroscopic rotator cuff repair. Methods The Mariner data set of the PearlDiver database from 2010 to 2022 was used to identify patients aged 40 to 65 years who underwent rotator cuff repair (identified by ...
Lee CS +4 more
europepmc +2 more sources
Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review. [PDF]
Clin Pharmacol TherLimited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Alatawi W +6 more
europepmc +2 more sources
Penggunaan ACE-Inhibitor untuk Mengurangi Proteinuria pada Sindrom Nefrotik [PDF]
, 2015 Proteinuria merupakan faktor prognostik penting dalam progresivitas sindrom nefrotik. Penggunaan ACE-inhibitor dapat mengurangi proteinuria dengan menurunkan tekanan hidrolikglomerular pada kelainan ginjal.
Prabu, O. G. (Oryza) +1 more
core +2 more sources
The potential therapeutic use of renin-angiotensin system inhibitors in the treatment of inflammatory diseases [PDF]
, 2019 Inflammation is a normal part of the immune response to injury or infection but its dysregulation promotes the development of inflammatory diseases, which cause considerable human suffering.
Avan, Amir +5 more
core +1 more source
ACE inhibitor fosinopril in the treatment of hypertension: potential benefits
Медицинский совет, 2014 Fosinopril with dual clearance can be used in renal failure without dose correction, which may be required in diabetes or elderly patients even with normal creatinine level in blood plasma.
AO Konradi
doaj +1 more source
Pharmacological effects of raas blockade in ischemic nephropathy [PDF]
, 2016 Background: The management of ischemic nephropathy due to atherosclerotic renal artery stenosis has become increasingly conservative in the modern era, with current guidelines recommending optimized medical therapy as the initial step.
Barbano, Biagio +8 more
core +1 more source
Рациональная фармакотерапия в кардиологии, 2016 Aim. To study dynamics of the indices of heart rate variability (HRV) and heart remodeling in response on combined therapy with fosinopril and simvastatin in postmenopausal metabolic syndrome (MS). Material and methods. 95 women were dynamically examined
I. V. Logacheva +2 more
doaj +1 more source
Рациональная фармакотерапия в кардиологии, 2016 Aim. To estimate effects of fosinopril and atenolol on autonomic regulation of heart in patients with arterial hypertension (HT) on the basis of spectral characteristics of heart rate variability (HRV).Material and methods.
A. R. Kiselyov +6 more
doaj +1 more source