Synergistic in-vitro activity of Fosinopril alone and in combination with imidocarb dipropionate against Babesia bovis [PDF]
Frontiers in Veterinary ScienceBovine babesiosis, caused by Babesia bovis is a major cattle disease worldwide, particularly in tropical and subtropical regions. A commonly used drug for the control and treatment of babesiosis is imidocarb dipropionate (ID), which has proved effective ...
Biswajit Bhowmick +6 more
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Fosinopril mediates antitumor efficacy by inducing GSDME-dependent pyroptosis in NSCLC [PDF]
Cell Death DiscoveryRepurposing existing drugs offers a promising approach to cancer therapy. Fosinopril, an angiotensin converting enzyme inhibitor (ACEI) approved for hypertension, has demonstrated antitumor effects in hepatocellular carcinoma.
Yue Gao +10 more
doaj +2 more sources
A Comprehensive Review on the Efficacy of Antihypertensives in Patients With End‐Stage Renal Disease [PDF]
International Journal of Hypertension, Volume 2026, Issue 1, 2026.End‐stage renal disease (ESRD) patients are particularly susceptible to hypertension, as blood pressure (BP) dysregulation leads to increased mortality and morbidity, especially considering the heightened risk of cardiovascular complications, including myocardial infarction, stroke, and congestive heart failure. Given the lack of specific guidelines on
Oluwakorede Akele +10 more
wiley +2 more sources
Российский кардиологический журнал, 2006 The aim of the study was to assess therapeutic effects offosinopril on intravascular platelet (PL) activity inpatients with arterial hypertension (AH) and metabolic syndrome (MS). Thirty-three patients received fosinopril (10 mg/d) for 4 months. Dynamics
I. N. Medvedev, V. V. Tolmachev
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Linking FHIR‐Based Medication Data to a Computable Algorithm for Heart Medication Optimization: A Critical Component of Any Medication Learning Health System [PDF]
Learning Health Systems, Volume 10, Issue 1, January 2026.ABSTRACT Introduction Despite strong evidence supporting guideline‐directed medical therapy (GDMT) for heart failure with reduced ejection fraction (HFrEF), a significant gap persists in the consistent application of these therapies. This shortfall has prompted organizations like the American College of Cardiology to recommend leveraging electronic ...
Joey LeGrand +5 more
wiley +2 more sources
International Journal of Endocrinology, 2019 Background and Objectives. Thyroid hormones have an important role in the growth and development of various tissues including the kidney, which is the major site of renin release and the consequent angiotensin and aldosterone formation.
Susan A. S. Farhadi, Kawa F. Dizaye
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Comparative Effect of Lisinopril and Fosinopril in Mitigating Learning and Memory Deficit in Scopolamine-Induced Amnesic Rats [PDF]
Advances in Pharmacological Sciences, 2015 Lisinopril and fosinopril were compared on scopolamine-induced learning and memory deficits in rats. A total of eighty-four male Wistar rats were divided into seven groups.
Debasree Deb +3 more
doaj +2 more sources
Utilization and Dose Optimization of Angiotensin‐Converting Enzyme Inhibitors in Heart Failure Patients With Reduced Ejection Fraction: A Cross Sectional Study on Implications for Guideline‐Targeted Therapy [PDF]
Health Science Reports, Volume 8, Issue 11, November 2025.ABSTRACT Background and Aims Angiotensin‐converting enzyme inhibitors (ACEIs) are well established in reducing morbidity and mortality among patients with chronic heart failure (CHF). Evidence has consistently supported the use of high‐dose ACEI therapy, which is recommended to optimize clinical outcomes and enhance patients' quality of life ...
Martin Kampamba +5 more
wiley +2 more sources
Angiotensinogen II Receptor Blockers May Decrease Risk of Adhesive Capsulitis After Rotator Cuff Repair [PDF]
Arthroscopy, Sports Medicine, and Rehabilitation, Volume 7, Issue 4, August 2025.Purpose To determine the effect of commonly prescribed antifibrotic medications on the odds of developing adhesive capsulitis (AC) following arthroscopic rotator cuff repair. Methods The Mariner data set of the PearlDiver database from 2010 to 2022 was used to identify patients aged 40 to 65 years who underwent rotator cuff repair (identified by ...
Cody S. Lee +4 more
wiley +2 more sources
Fosinopril inhibits Ang II-induced VSMC proliferation, phenotype transformation, migration, and oxidative stress through the TGF-β1/Smad signaling pathway [PDF]
Open Life SciencesFosinopril (FOS) is an angiotensin-converting enzyme inhibitor that can decrease angiotensin II (Ang II) formation, thereby reducing systemic vasoconstriction.
Chen Siqi, Ye Lingxiang
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