Results 51 to 60 of about 4,513 (219)

Micro-RNA family that modulates fibrosis and uses thereof [PDF]

open access: yes, 2017
The present invention relates to the identification of a microRNA family, designated miR-29a-c, that is a key regulator of fibrosis in cardiac tissue. The inventors show that members of the miR-29 family are down-regulated in the heart tissue in response
Olson, Eric N., van Rooij, Eva
core   +1 more source

Drug‐Induced Liver Injury in Patients With Chronic Liver Disease

open access: yesLiver International, Volume 45, Issue 3, March 2025.
ABSTRACT Objective Drug‐induced liver injury (DILI) is a global problem and can develop from exposure to prescription or over‐the‐counter medications as well as herbal and dietary supplements. The diagnosis of DILI is clinically challenging, and liver injury can be severe leading to liver failure, death, or liver transplantation.
Marwan Ghabril   +2 more
wiley   +1 more source

The role of fosinopril in the treatment and prevention of cardiovascular diseases

open access: yesМедицинский совет, 2015
In Russia, cardiovascular diseases account for 57% of deaths in the overall mortality. Arterial hypertension (AH) is one of the main risk factors (RF) for cardiovascular diseases (along with dyslipidemia, smoking, metabolic syndrome, diabetes mellitus ...
G. A. Baryshnikova
doaj   +1 more source

The effect of acute consumption of a flavonol-rich cocoa drink on cerebral vasomotor reactivity in African Americans [PDF]

open access: yes, 2014
textAfrican Americans (AA) are at great risk of cardiovascular diseases (CVD) which can lead to brain damage, dementia, and endothelial dysfunction.
Ku, ByungMo
core  

Genetic polymorphisms influencing antihypertensive drug responses

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 4, Page 929-950, February 2025.
Abstract Hypertension is a major contributor to cardiovascular disease and its associated morbidity and mortality. The low efficacy observed with some anti‐hypertensive therapies has been attributed partly to inter‐individual genetic variability. This paper reviews the major findings regarding these genetic variabilities that modulate responses to anti‐
Jana El Cheikh   +4 more
wiley   +1 more source

Intravascular platelet activity correction by fosinopril in arterial hypertension patients with metabolic syndrome

open access: yesРоссийский кардиологический журнал, 2006
The aim of the study was to assess therapeutic effects offosinopril on intravascular platelet (PL) activity inpatients with arterial hypertension (AH) and metabolic syndrome (MS). Thirty-three patients received fosinopril (10 mg/d) for 4 months. Dynamics
I. N. Medvedev, V. V. Tolmachev
doaj  

Serum cystatin C and chemerin levels in diabetic retinopathy [PDF]

open access: yes, 2017
Peer reviewedPublisher ...
Chen, Xuedong   +5 more
core  

Micro-RNAS that control myosin expression and myofiber identity [PDF]

open access: yes, 2015
The present invention relates to the identification of two microRNAs, miR-499 and miR-208b, that repress fast skeletal muscle contractile protein genes. Expression of miR-499 and/or miR-208b can be used to repress fast fiber genes and activate slow fiber
Olson, Eric N., van Rooij, Eva
core   +1 more source

Impact of Renin–Angiotensin–Aldosterone System (RAAS) Gene Polymorphism in Essential Hypertension and Antihypertensive Drug Therapy: A Review

open access: yesInternational Journal of Hypertension, Volume 2025, Issue 1, 2025.
Genetic, demographic and environmental factors all play a role in the frequency of an intricate multifactorial condition known as hypertension. Approximately 30% and 50% of BP fluctuation are influenced by genetic variability. Many genetic studies have confirmed the link between genetic variability and susceptibility to essential hypertension; hence ...
Archana Adhikari   +6 more
wiley   +1 more source

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