Results 71 to 80 of about 4,513 (219)

Comparison of chemical clustering methods using graph- and fingerprint-based similarity measures [PDF]

open access: yes, 2003
This paper compares several published methods for clustering chemical structures, using both graph- and fingerprint-based similarity measures. The clusterings from each method were compared to determine the degree of cluster overlap. Each method was also
Blankley, C.J.   +2 more
core   +1 more source

Tools for clinical pharmacists to identify medications that can cause drug‐induced cognitive impairment: A systematic review

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 7, Issue 12, Page 1207-1227, December 2024.
Abstract Cognitive impairment affects around 19% of community‐dwelling older adults in the United States. Pharmacists can play a significant role in identifying and deprescribing cognitive‐impairing medications through cognitive‐focused medication reviews or as part of comprehensive medication management.
Jacob Stanton   +4 more
wiley   +1 more source

Renin-angiotensin system blockers: therapy of choice in patients with arterial hypertension and heart failure

open access: yesМедицинский совет, 2013
One of the major challenges in the modern medicine is chronic heart failure (CHF) characterized by high incidence, really unfavourable prognosis and high cost of treatment.
G. N. Gorokhovskaya   +2 more
doaj   +1 more source

Изменение фосфолипидного спектра мембран под влиянием гипотензивной терапии при хронической болезни почек [PDF]

open access: yes, 2013
На примере обследования больных с артериальной гипертензией при хронической болезни почек определены изменения фосфолипидного спектра мембран и их динамика под влиянием гипотензивной терапии фозиноприлом и/или дилтиаземомyesБелгородский ...
Демихова, Н. В.   +2 more
core  

Association between prescription drugs and all‐cause mortality risk in the UK population

open access: yesAging Cell, Volume 23, Issue 12, December 2024.
The UK Biobank has collected data on prescription medications and mortality for over 500,000 participants aged 40–70 years. We analyzed the effects of the top 406 prescribed medications on overall mortality rates in the general population. Most drugs were linked to a shortened lifespan, likely due to the life‐limiting nature of the diseases they are ...
Jonas Morin   +4 more
wiley   +1 more source

EFFECT OF ACE INHIBITOR AND RECEPTOR ANTAGONIST OF TYPE 1 ANGIOTENSIN II ON HEMODYNAMICS AND MORPHO-FUNCTIONAL PARAMETERS OF THE HEART IN PATIENTS WITH HEART FAILURE ON A BACKGROUND OF CORONARY HEART DISEASE COMBINED WITH TYPE 2 DIABETES

open access: yesКубанский научный медицинский вестник, 2017
Aim. The article discusses the evaluation of the effect of 3-month therapy of angiotensin-converting enzyme fosinopril and angiotensin II receptor antagonists valsartan on the clinical manifestations of CHF, hemodynamics and morphofunctional parameters ...
Z. V. BITAROVA   +2 more
doaj   +1 more source

Limited evidence for the usage of renin–angiotensin–aldosterone pathway blockers to prevent arthrofibrosis after total knee arthroplasty. A systematic review of clinical evidence

open access: yesJournal of Experimental Orthopaedics, Volume 11, Issue 4, October 2024.
Abstract Purpose Despite advances in surgical techniques and rehabilitation protocols, arthrofibrosis following total knee arthroplasty (TKA) still has poor outcomes. In the last decade, attention has been focused on the pathogenesis and cascade of events leading to the development of fibrosis.
Giuseppe Anzillotti   +7 more
wiley   +1 more source

VALUE OF THERAPEUTIC EQUIVALENCE IN SUBSTITUTION OF ORIGINAL DRUG WITH GENERIC BY EXAMPLE OF FOSINIPRIL

open access: yesРациональная фармакотерапия в кардиологии, 2016
Aim. To study the therapeutic equivalence of original and generic fosinopril in patients with arterial hypertension (HT) of 1-2 degrees, and to evaluate the cost effectiveness of original drug substitution with generic. Material and methods.
N. P. Kutishenko   +3 more
doaj   +1 more source

ACE-inhibition ameliorates vascular reactivity and delays diabetes outcome in NODmice. [PDF]

open access: yes, 2008
Recently, we have demonstrated a direct correlation among hyperglycaemia, vascular dysfunction and eNOS post-translational regulation in non non-obese diabetic mice (NOD).
Brancaleone, V   +6 more
core   +1 more source

Metal–Organic Frameworks in Surface Enhanced Raman Spectroscopy–Based Analysis of Volatile Organic Compounds

open access: yesAdvanced Science, Volume 11, Issue 30, August 14, 2024.
The integration of Metal–Organic Frameworks (MOF) into Surface‐Enhanced Raman Spectroscopy (SERS) sensors is discussed, focusing on the complex interplay of both worlds, and elucidating respective design rules for maximizing the analytical performance of the platform.
Juan A. Allegretto, Jakub Dostalek
wiley   +1 more source

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