Results 71 to 80 of about 180 (132)
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Reactions Weekly, 1997
Fosinopril is a phosphorus-containing ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor. It is hydrolysed mainly in the gastrointestinal mucosa and liver to the active diacid, fosinoprilat, which has unique pharmacological properties. The majority of the active moieties of other ACE inhibitors are excreted in the urine.
H, Shionoiri +6 more
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Fosinopril is a phosphorus-containing ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor. It is hydrolysed mainly in the gastrointestinal mucosa and liver to the active diacid, fosinoprilat, which has unique pharmacological properties. The majority of the active moieties of other ACE inhibitors are excreted in the urine.
H, Shionoiri +6 more
openaire +3 more sources
The American Journal of Cardiology, 1993
Angiotensin-converting enzyme (ACE) inhibitors are an effective, well-tolerated option for management of mild-to-moderate hypertension. An increase of nearly 250% in prescriptions between 1986 and 1990 testifies to the growing importance of this drug class.
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Angiotensin-converting enzyme (ACE) inhibitors are an effective, well-tolerated option for management of mild-to-moderate hypertension. An increase of nearly 250% in prescriptions between 1986 and 1990 testifies to the growing importance of this drug class.
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Inpharma Weekly, 1992
Fosinopril, the first agent in a new chemical class of phosphorus-containing angiotensin-converting enzyme (ACE) inhibitors, has unique pharmacologic properties. Fosinopril administration leads to complete inhibition of plasma ACE activity for 12-24 h.
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Fosinopril, the first agent in a new chemical class of phosphorus-containing angiotensin-converting enzyme (ACE) inhibitors, has unique pharmacologic properties. Fosinopril administration leads to complete inhibition of plasma ACE activity for 12-24 h.
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Fosinopril Overdose in an Infant
Journal of Pharmacy Technology, 1999Objective: To report an accidental fosinopril overdose in an infant. Case Summary: A 20-month-old African-American girl ingested approximately 16 mg/kg of fosinopril. Following aggressive gastric decontamination, the patient experienced an uneventful hospital course.
Kimberly A Stokes +2 more
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Drugs, 1996
Fosinopril is a phosphinic acid derivative which undergoes rapid hydrolysis after oral administration to the active diacid ACE inhibitor fosinoprilat. Cardiotropic effects have been associated with the drug, and the compensatory dual elimination route of fosinopril via renal and hepatic systems offers an opportunity for ACE inhibitor treatment of ...
A J, Wagstaff, R, Davis, D, McTavish
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Fosinopril is a phosphinic acid derivative which undergoes rapid hydrolysis after oral administration to the active diacid ACE inhibitor fosinoprilat. Cardiotropic effects have been associated with the drug, and the compensatory dual elimination route of fosinopril via renal and hepatic systems offers an opportunity for ACE inhibitor treatment of ...
A J, Wagstaff, R, Davis, D, McTavish
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Fosinopril as a Possible Pemphigus-Inducing Drug
Dermatology, 2002Fosinopril has recently been added to the angiotensin-converting enzyme inhibitors inducing pemphigus. The observation of a patient in whom pemphigus vulgaris (PV) worsened after taking fosinopril prompted us to study an experimental way to assess its responsibility.
PARODI, AURORA +4 more
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Clinical Pharmacology of Fosinopril
Drug Investigation, 1991Fosinopril is a novel phosphorus-containing angiotensin-converting enzyme (ACE) inhibitor which is distinguished from the majority of established ACE inhibitors by its beneficial effect on cardiac and renal haemodynamics in patients with essential hypertension and by a combination of pharmacokinetic properties — long plasma elimination half-life, dual ...
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2008
Fosinopril is an acyloxyalkyl ester of fosinoprilat, a phosphinic acid angiotensin-converting enzyme (ACE) inhibitor developed for the treatment of hypertension and congestive heart failure. The hydroxylphosphinylacetyl proline class of inhibitors exhibits high affinity for ACE and a high degree of efficacy for inhibition of the angiotensin I-induced ...
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Fosinopril is an acyloxyalkyl ester of fosinoprilat, a phosphinic acid angiotensin-converting enzyme (ACE) inhibitor developed for the treatment of hypertension and congestive heart failure. The hydroxylphosphinylacetyl proline class of inhibitors exhibits high affinity for ACE and a high degree of efficacy for inhibition of the angiotensin I-induced ...
openaire +1 more source