Results 31 to 40 of about 1,470,646 (286)

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy   +5 more
wiley   +1 more source

Achieving good outcomes in foster care: a personal perspective on research across contexts and cultures.

open access: yesSocial Work and Society, 2017
This paper presents a brief synthesis of learning from recently published European foster care research, focussing especially on papers given at the 2015 Siegen foster care research conference.
June Thoburn
doaj   +2 more sources

Features of non-kinship foster care children with birth family contact in Andalusia [PDF]

open access: yes, 2019
The aim of the presentation is to describe the personal features of non-kinship foster care children who have visits with their birth family in Málaga, Granada and Jaén (provinces of Andalusia, Spain).
Bernedo-Muñoz, Isabel Maria   +5 more
core  

Treatment Decision‐Making Roles and Preferences Among Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Decision‐making (DM) dynamics between adolescents and young adults (AYAs) with cancer, parents, and oncologists remain underexplored in diverse populations. We examined cancer treatment DM preferences among an ethnically and socioeconomically diverse group of AYAs and their parents.
Amanda M. Gutierrez   +14 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Foster Parent Training for the Delivery of Independent Living Skills [PDF]

open access: yes, 2013
Master's Project (M.Ed.) University of Alaska Fairbanks, 2013Although training is made available to foster parents when they volunteer to share their homes with children in need, the required ten hours for single parents and fifteen hours for coupled ...
Alley, Kandy
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Foster Care in California: Achievements and Challenges [PDF]

open access: yes, 2010
Examines changes in California's foster care policies, processes, and practices; progress since 2000 in reducing the number of children in foster care; contributing factors; and remaining challenges, including issues of payments and aging ...
Caroline Danielson, Helen Lee
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

VIEWS OF FOSTERCHILDREN ABOUT CONTACTS WITH PARENTS AND RELATIVES

open access: yesHuman Research in Rehabilitation, 2016
This paper presents the results of research on the views of children about contacts with their birth parents and relatives. The views of children are seen through their experience in contacts and the wishes of children that relate to future contacts ...
Ljiljana Skrobić
doaj  

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