Results 31 to 40 of about 1,481,212 (294)

Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in how PPC is understood, operationalized, and integrated within pediatric oncology programs. In particular, ambiguity surrounding
Leeat Granek   +13 more
wiley   +1 more source

A Matter of Justice

open access: yesVoices in Bioethics, 2014
In April of 2001, I visited Emmanuel A. at the Incarnation Children’s Center (“ICC”). Emmanuel was one of my first clients.1 He had come into foster care at birth. His mother was young, a recent immigrant, addicted to heroin, and living in poverty.
Adira Hulkower
doaj   +1 more source

A 5-Year Projection of the Number of Children Reaching Age 18 While in Foster Care [PDF]

open access: yes, 2010
Estimates the number of children aging out of foster care in 2009-13. Examines recent trends by age of entry into foster care and outlines how changes in the number entering care, their age distribution, and duration of care affect ...
Fred Wulczyn, Linda Collins
core  

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Achieving good outcomes in foster care: a personal perspective on research across contexts and cultures.

open access: yesSocial Work and Society, 2017
This paper presents a brief synthesis of learning from recently published European foster care research, focussing especially on papers given at the 2015 Siegen foster care research conference.
June Thoburn
doaj   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Health Care for Our Troubled Youth: Provision of Services in the Foster Care and Juvenile Justice Systems of California [PDF]

open access: yes, 2002
Lack of access to high quality health care is a problem for most low-income people, but especially for young people in foster care and the juvenile justice system.
Barry Krisberg   +2 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

VIEWS OF FOSTERCHILDREN ABOUT CONTACTS WITH PARENTS AND RELATIVES

open access: yesHuman Research in Rehabilitation, 2016
This paper presents the results of research on the views of children about contacts with their birth parents and relatives. The views of children are seen through their experience in contacts and the wishes of children that relate to future contacts ...
Ljiljana Skrobić
doaj  

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