Results 51 to 60 of about 1,470,646 (286)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Data Snapshot on Foster Care Placement [PDF]
, 2011 Based on updated KIDS COUNT data, highlights the progress made on increasing placement of children in foster families rather than in institutions or group homes.
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Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
GROOTMOEDERS IN KAYAMANDI SE ERVARING VAN FAMILIEPLEEGSORG
Social Work/Maatskaplike Werk, 2006 Pleegplasings by familie as vorm van substituutsorg, is die vinnigs groeiende kindersorgdiens in die Verenigde State van Amerika (voorts genoem die VSA) as gevolg van ’n afname in geskikte pleegouers (Wilson & Chipunga, 1996:387).
Dora van Rensburg, Sulina Green
doaj +1 more source
Youth who "Age Out" of Foster Care: Troubled Lives, Troubling Prospects [PDF]
, 2001 If foster children, in general, are a population at risk, youth who age out of the system may be even more so. Research suggests that without the extended support most families provide young people in the transition to adulthood, youth leaving foster ...
Richard Wertheimer
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Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
How Do People Become Foster Carers in Portugal? The Process of Building the Motivation
Social Sciences, 2019 Act no. 142/2015 highlights the importance of children out-of-home being placed in a family context. However, foster care continues to be an almost absent component in the Portuguese childcare system.
Elisete Diogo, Francisco Branco
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Colloquium, 2020 The social and political transformation that occurred in Poland following the fall of the communist system has resulted in an intensive development of non-governmental organizations, including those offering services for children and families.
Piotr Kulikowski
doaj +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
FEBS Open Bio, EarlyView.Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source