Results 31 to 40 of about 1,870,692 (256)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Being a Foster Family in Portugal—Motivations and Experiences

open access: yesSocieties, 2017
Foster care is an almost absent component in the child care system and scientific research conducted in Portugal foster comprises 3.2%1 of out-of-home care in Portugal. This research aims to contribute to a deeper visibility of the care phenomena, giving
Elisete Diogo, Francisco Branco
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Facing disabilities in children with prenatal alcohol exposure: parenthood and stressors according to families and professionals' narratives

open access: yesFrontiers in Sociology
BackgroundPrenatal alcohol exposure can cause neurodevelopmental disorders affecting children's brain function, educational and social skills throughout their lives.
Laurence Simmat-Durand   +1 more
doaj   +1 more source

Adaptation Issues in Disabled Children Deprived of Parental Care, Living in Foster Families

open access: yesПсихологическая наука и образование, 2017
The paper focuses on revealing psychological issues in the adaptation of children, including the ones with disabilities, which are deprived of parental care and are raised in foster families.
Shulga T.I.
doaj   +1 more source

The influence of feed quality on the development and productivity of bee queens

open access: yesНауковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Гжицького. Серія: Сільськогосподарські науки, 2021
The research aimed to study the effect of additional protein feeding of foster families with buckwheat stalks. The research was conducted during the summer period in 2020 and 2021. Ten foster families were selected for the experiment.
Yu. Kovalskyi   +4 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Socio-perceptual images as regulators of child-parental relations in foster families

open access: yesСоциальная психология и общество, 2021
Objective. Definition of communications of I-images of mothers with He-images of the own children, I-images of the foster mothers with He-images of foster children became the purpose of our research; establishment of communications of I-images of the ...
Sitnikov V.L.   +3 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

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