Results 41 to 50 of about 123,550 (297)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Fostering Collaboration in the Management of Family Finances
Proceedings of the Annual Meeting of the Australian Special Interest Group for Computer Human Interaction, 2015 Managing finances is a practice carried out daily in homes across the world. Despite this, the practice is not yet a strong focus for HCI work in the home. This paper looks specifically at the ways that families organise and manage their finances.
Stephen Snow, Dhaval Vyas
openaire +4 more sources
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Being a Foster Family in Portugal—Motivations and Experiences
Societies, 2017 Foster care is an almost absent component in the child care system and scientific research conducted in Portugal foster comprises 3.2%1 of out-of-home care in Portugal. This research aims to contribute to a deeper visibility of the care phenomena, giving
Elisete Diogo, Francisco Branco
doaj +1 more source
Вестник университета, 2022 The article discusses a special and effective form of living arrangements for the elderly and disabled in a foster family in the regional entities of the Russian Federation. The experience of organizing a foster or substitute family has been developed in
R. M. Sadykov, N. L. Bolshakova
doaj +1 more source
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Adaptation Issues in Disabled Children Deprived of Parental Care, Living in Foster Families
Психологическая наука и образование, 2017 The paper focuses on revealing psychological issues in the adaptation of children, including the ones with disabilities, which are deprived of parental care and are raised in foster families.
Shulga T.I.
doaj +1 more source
Children, 2021 Children in foster care have a high prevalence of attention deficit and hyperactivity disorder (ADHD) diagnosis, together with other difficulties in inattentive/hyperactive behaviors, executive and cognitive processes.
María Peñarrubia +3 more
doaj +1 more source
Exploratory study of risks to stability in foster and kinship care in NSW [PDF]
, 2013 This report describes an exploratory study on various aspects and risks to stability in foster and kinship placements.The report finds that compared to foster care, risks to placement stability are more evident for kinship care.
Marilyn McHugh
core
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source