Results 71 to 80 of about 6,114,030 (297)

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

Foster Care and Education

, 2008
Why do foster children perform badly at school? There is no evident answer to that question. Very little research has been performed in Sweden. According to the Swedish Education Act, all children and youths shall have equal access to education.
Höjer, Ingrid,
core   +1 more source

Experience and Perceptions of Changes in the Living Environment by Older People Losing Their Autonomy: A Qualitative Study in the Caribbean

Risk Management and Healthcare Policy, 2021
Rita Chammem,1,2 Serge Domi,2 Claire Della Vecchia,1 Thomas Gilbert,1,3 Anne-Marie Schott1,3 1University of Claude Bernard Lyon 1, HESPER Laboratory, Lyon, EA 7425, France; 2CRIFONDO, Caribbean Renaissance Initiative, Département de Gé ...
Chammem R, Domi S, Della Vecchia C, Gilbert T, Schott AM   +4 more
doaj  

A Reconfigurable Memristive Spiking Neuron Enabling Advanced Neuromorphic Computing

Advanced Science, EarlyView.
Pek Jun Tiw and co‐workers develop a reconfigurable memristive neuron that can exhibit four spiking behaviors with freely tunable spike train parameters. The neuron supports multiplexed spike encoding of multiple pieces of information. It also supports advanced neural network strategies, such as neural heterogeneity and dynamic mode switching ...
Pek Jun Tiw, Yuqi Li, Zhongyuan Li, Qihang Ding, Yuzhe Wang, Jiarong Wang, Yuchao Yang   +6 more
wiley   +1 more source

Child Protection and Adult Crime: Using Investigator Assignment to Estimate Causal Effects of Foster Care [PDF]

Nearly 20% of young prison inmates spent part of their youth in foster care - the placement of abused or neglected children with substitute families. Little is known whether foster care placement reduces or increases the likelihood of criminal behavior ...
Joseph J. Doyle, Jr.
core  

Indigenous Young People Transitioning from Out-of-Home Care (OOHC) in Victoria, Australia: The Perspectives of Workers in Indigenous-Specific and Non-Indigenous Non-Government Services

International Indigenous Policy Journal, 2016
Indigenous children and young people are overrepresented in the Australian out-of-home care (OOHC) system. To date, specific research has not been undertaken on workers' perspectives regarding the Indigenous-specific and non-Indigenous supports and ...
Philip Mendes, Bernadette Saunders, Susan Baidawi   +2 more
doaj   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

TV in a foster home, [foster home]

, 2018
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Social Policy Archive, Jaggs, Donella
core  

SOCAV: a nurse-led support programme for self-direction in people with dementia receiving home care, involving informal caregivers – a feasibility study with process evaluation in the Netherlands

BMJ Open
Objectives To adapt the SOCAV programme—originally developed for residential dementia care—for home care use, and to evaluate its feasibility and potential to foster behavioural change in nurses and informal caregivers supporting self-direction in people
Maud Graff, Phébe Das, Gerbrich Douma, Hanneke Donkers, Lieve Roets-Merken   +4 more
doaj   +1 more source

Tumor Mechanical Remodeling via Bidirectional Calcium Redistribution Enables Deep Photothermal‐Immunotherapy

Advanced Science, EarlyView.
A bidirectional calcium‑redistributing nanomodulator rewires intra‑extracellular calcium homeostasis to remodel tumor mechanical microenvironments. It softens tumor stroma to facilitate deep tissue penetration while stiffening tumor cells, evoking amplified immunogenic cell death and robust CTL infiltration, which achieves potent deep photothermal ...
Hongjuan Zhao, Jinpei Sun, Chenxi Zhao, Yuting Cang, Keyu Zong, Yuxin Guo, Yajing Wang, Di Meng, Qingling Song, Lei Wang   +9 more
wiley   +1 more source